ArticleJournal of mathematical biology2021
The impact of infection-derived immunity on disease dynamics.
Article in Journal of mathematical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Clinical Burden of Disease and Demographics in Older Adults Hospitalized with RSV Infection in England: A Retrospective Cohort Study.Infectious diseases and therapy · 2026Article
- Infected host competence overshadows heterogeneity in susceptibility in shaping experimental epizootics.Ecology · 2026Article
- Prior pathogen exposure augments inter-individual heterogeneity in antibody levels and reinfection loads in a songbird-pathogen system.Scientific reports · 2026Article
- Host Prior Exposure Augments Gene Expression Heterogeneity of Both Host and Pathogen During In Vivo Infection.Molecular ecology · 2026Article
- Article
- Infected host competence overshadows heterogeneity in susceptibility in shaping experimental epizootics.bioRxiv : the preprint server for biology · 2025Article
- Host prior exposure augments heterogeneity in gene expression in both host and pathogen duringbioRxiv : the preprint server for biology · 2025Article
- Leaky or polarised immunity: Non-Markovian modelling highlights the impact of immune memory assumptions.PLoS computational biology · 2025Article
- Reinfection with a Bacterial Pathogen Augments Heterogeneity in Host Disease Responses.Research square · 2025Article
- Pathogen priming alters host transmission potential and predictors of transmissibility in a wild songbird species.mSphere · 2025Article
- Eco-evolutionary dynamics of pathogen immune-escape: deriving a population-level phylodynamic curve.Journal of the Royal Society, Interface · 2025Article
- Pathogen priming alters host transmission potential and predictors of transmissibility in a wild songbird species.bioRxiv : the preprint server for biology · 2024Article
- Prior exposure to pathogens augments host heterogeneity in susceptibility and has key epidemiological consequences.PLoS pathogens · 2024Article
- Prior exposure to pathogens augments host heterogeneity in susceptibility and has key epidemiological consequences.bioRxiv : the preprint server for biology · 2024Article
- A novel indicator in epidemic monitoring through a case study of Ebola in West Africa (2014-2016).Scientific reports · 2024Article
- The impact of cross-reactive immunity on the emergence of SARS-CoV-2 variants.Frontiers in immunology · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
When modeling infectious diseases, it is common to assume that infection-derived immunity is either (1) non-existent or (2) perfect and lifelong. However there are many diseases in which infection-derived immunity is known to be present but imperfect. There are various ways in which infection-derived immunity can fail, which can ultimately impact the probability that an individual be reinfected by the same pathogen, as well as the long-run population-level prevalence of the pathogen. Here we discuss seven different models of imperfect infection-derived immunity, including waning, leaky and all-or-nothing immunity. For each model we derive the probability that an infected individual becomes reinfected during their lifetime, given that the system is at endemic equilibrium. This can be thought of as the impact that each of these infection-derived immunity failures have on reinfection. This measure is useful because it provides us with a way to compare different modes of failure of infection-derived immunity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.