Evidence map›Paper›PMID 34773092›Full record

ArticleEuropean journal of clinical nutrition2022

Vitamin D status and obesity in children from Chile.

Francisco Pérez-Bravo, Lissette Duarte, Miguel Arredondo-Olguín, Germán Iñiguez, Oscar Castillo-Valenzuela

Open access · hybridAbstract read
In one paragraph

Article in European journal of clinical nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Sleep Duration and Sun Exposure in Portuguese Children: Associations With Obesity Indicators.American journal of human biology : the official journal of the Human Biology Council · 2026
    Article
  4. Effect of Excess Weight on 25-Hydroxyvitamin D Levels.Turkish archives of pediatrics · 2025
    Article
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  9. Effects ofNutrients · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Francisco Pérez-BravoInstitute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile.ORCID http://orcid.org/0000-0002-5660-5717
Lissette DuarteNutrigenomics Laboratory, Nutrition Department, Faculty of Medicine, University of Chile, Santiago, Chile.
Miguel Arredondo-OlguínInstitute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile.
Germán IñiguezMaternal and Child Research Institute (IDIMI), School of Medicine, University of Chile, Santiago, Chile.ORCID http://orcid.org/0000-0002-9247-2982
Oscar Castillo-ValenzuelaNutrition and Dietetics School, Universidad Finis Terrae, Santiago, Chile. ocastillo@uft.cl.ORCID http://orcid.org/0000-0002-4411-8655
University of Chile · CLFinis Terrae University · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin D [25(OH)D] is essential for normal bone development and maintenance. Furthermore, its deficiency has been associated with obesity, cardiovascular diseases, insulin resistance, autoimmune diseases, and certain cancers.

objectiveTo determine the incidence of serum 25(OH)D deficiency (<20 ng/ml) among apparently healthy Chilean children (4-14 years old) from three Chilean geographic areas during May-September 2018. MATERIALS AND

methodsSerum 25(OH)D levels were measured by a competitive protein-binding ELISA assay in 1134 children, and correlations between serum 25(OH)D levels, BMI, and geographic area were calculated. Individuals were grouped according to their serum 25-hydroxyvitamin D levels (ng/ml): severe deficiency: <5; moderate deficiency: 5-10.9; mild deficiency: 11-20.9; insufficiency: 21-29.9 and sufficiency: 30-100.

resultsWe found 80.4% of children had serum 25(OH)D deficiency, with 1.7% severe, 24.6% moderate, and 54.1% mild. In the three cities, the percentage of serum 25(OH)D deficit was increased when comparing overweight or obesity with a healthy weight. Additionally, an interaction effect was observed between geographic area, nutritional status, and serum 25(OH)D levels using the factorial ANOVA test (p = 0.038). In Antofagasta, there were more overweight children and also a higher percentage of children with VitD deficiency (<30 ng/ml) compared to Santiago or Concepción.

conclusionThis study revealed a high prevalence of serum 25(OH)D deficiency in children between 4 and 14 years old in Chile (80.4%) during May-September 2018. Obese and overweight children had the highest prevalence of serum 25(OH)D deficiency.

Indexed as

Pediatric ObesityVitamin D DeficiencyAdolescentBody Mass IndexChildChild, PreschoolChileHumansOverweightPrevalenceVitamin DVitaminsVitamin DVitamins

Identifiers

PMID34773092
PMCPMC9187513
OpenAlexW3213207875

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.