Evidence map›Paper›PMID 34773064›Full record

ArticleCommunications biology2021

Archaeogenetic analysis of Neolithic sheep from Anatolia suggests a complex demographic history since domestication.

Erinç Yurtman, Onur Özer, Eren Yüncü, Nihan Dilşad Dağtaş, Dilek Koptekin, Yasin Gökhan Çakan, Mustafa Özkan, Ali Akbaba, Damla Kaptan, Gözde Atağ and 32 more

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 41 citations in OpenAlex.

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  12. Phenotype transition from wild mouflon to domestic sheep.Genetics, selection, evolution : GSE · 2024
    Review
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  16. Genomic perspectives on human dispersals during the Holocene.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  17. Article
  18. An endemic pathway to sheep and goat domestication at Aşıklı Höyük (Central Anatolia, Turkey).Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors at 16 institutions in 7 countries.

Erinç Yurtman *Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Onur Özer *Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Eren Yüncü *Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Nihan Dilşad DağtaşDepartment of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Dilek KoptekinDepartment of Health Informatics, Middle East Technical University, Ankara, Turkey.ORCID http://orcid.org/0000-0003-2664-5774
Yasin Gökhan ÇakanDepartment of Prehistory, Istanbul University, Laleli, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-4919-7129
Mustafa ÖzkanDepartment of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Ali AkbabaDepartment of Anthropology, Ankara University, Ankara, Turkey.
Damla KaptanDepartment of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Gözde AtağDepartment of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Kıvılcım Başak VuralDepartment of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Can Yümni GündemDepartment of Archaeology, Batman University, Batman, Turkey.
Louise MartinInstitute of Archaeology, University College London, London, UK.
Gülşah Merve KılınçDepartment of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Ayshin GhalichiDepartment of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Sinan Can AçanDepartment of Biological Sciences, Middle East Technical University, Ankara, Turkey.ORCID http://orcid.org/0000-0002-5534-0024
Reyhan YakaDepartment of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Ekin SağlıcanDepartment of Biological Sciences, Middle East Technical University, Ankara, Turkey.ORCID http://orcid.org/0000-0001-8646-1163
Vendela Kempe LagerholmArchaeological Research Laboratory, Department of Archaeology and Classical Studies, University of Stockholm, Stockholm, Sweden.
Maja KrzewińskaArchaeological Research Laboratory, Department of Archaeology and Classical Studies, University of Stockholm, Stockholm, Sweden.
Torsten GüntherDepartment of Organismal Biology, Human Evolution Research Program, Uppsala University, Uppsala, Sweden.
Pedro Morell MirandaDepartment of Organismal Biology, Human Evolution Research Program, Uppsala University, Uppsala, Sweden.
Evangelia PişkinDepartment of Settlement Archaeology, Middle East Technical University, Ankara, Turkey.
Müge ŞevketoğluCentre for Archaeology, Cultural Heritage and Conservation, Cyprus International University, Nicosia, Cyprus.
C Can BilginDepartment of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Çiğdem AtakumanDepartment of Settlement Archaeology, Middle East Technical University, Ankara, Turkey.
Yılmaz Selim ErdalDepartment of Anthropology, Hacettepe University, Ankara, Turkey.
Elif SürerDepartment of Modeling and Simulation, Graduate School of Informatics, Middle East Technical University, Ankara, Turkey.ORCID http://orcid.org/0000-0002-0738-6669
N Ezgi AltınışıkDepartment of Anthropology, Hacettepe University, Ankara, Turkey.
Johannes A LenstraFaculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.ORCID http://orcid.org/0000-0003-1745-7739
Sevgi YorulmazDepartment of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Mohammad Foad AbazariResearch Center for Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-3383-8526
Javad HoseinzadehDepartment of Archaeology, University of Kashan, Kashan, Iran.ORCID http://orcid.org/0000-0002-1954-8389
Douglas BairdDepartment of Archaeology, Classics, and Egyptology, University of Liverpool, Liverpool, UK.ORCID http://orcid.org/0000-0001-8651-5272
Erhan BıçakçıDepartment of Prehistory, Istanbul University, Laleli, Istanbul, Turkey.
Özlem ÇevikDepartment of Archaeology, Trakya University, Edirne, Turkey.
Fokke GerritsenNetherlands Institute in Turkey, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-6665-1928
Rana ÖzbalDepartment of Archaeology and History of Art, Koç University, Istanbul, Turkey.
Anders GötherströmArchaeological Research Laboratory, Department of Archaeology and Classical Studies, University of Stockholm, Stockholm, Sweden.
Mehmet SomelDepartment of Biological Sciences, Middle East Technical University, Ankara, Turkey. msomel@metu.edu.tr.ORCID http://orcid.org/0000-0002-3138-1307
İnci ToganDepartment of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Füsun ÖzerDepartment of Anthropology, Hacettepe University, Ankara, Turkey. fusunozer@hacettepe.edu.tr.ORCID http://orcid.org/0000-0003-0443-5805
Middle East Technical University · TRHacettepe University · TRStockholm University · SEIstanbul University · TRUppsala University · SEAnkara University · TRBatman University · TRCyprus International University · CYKoç University · TRNetherlands Institute in Turkey · TRTehran University of Medical Sciences · IRTrakya University · TRUniversity College London · GBUniversity of Kashan · IRUniversity of Liverpool · GBUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sheep were among the first domesticated animals, but their demographic history is little understood. Here we analyzed nuclear polymorphism and mitochondrial data (mtDNA) from ancient central and west Anatolian sheep dating from Epipaleolithic to late Neolithic, comparatively with modern-day breeds and central Asian Neolithic/Bronze Age sheep (OBI). Analyzing ancient nuclear data, we found that Anatolian Neolithic sheep (ANS) are genetically closest to present-day European breeds relative to Asian breeds, a conclusion supported by mtDNA haplogroup frequencies. In contrast, OBI showed higher genetic affinity to present-day Asian breeds. These results suggest that the east-west genetic structure observed in present-day breeds had already emerged by 6000 BCE, hinting at multiple sheep domestication episodes or early wild introgression in southwest Asia. Furthermore, we found that ANS are genetically distinct from all modern breeds. Our results suggest that European and Anatolian domestic sheep gene pools have been strongly remolded since the Neolithic.

Indexed as

DomesticationPolymorphism, GeneticAnimalsArchaeologyCell NucleusDemographyDNA, AncientDNA, MitochondrialSheep, DomesticTurkeyDNA, AncientDNA, Mitochondrial

Identifiers

PMID34773064
PMCPMC8589978
OpenAlexW3214089245

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.