ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022
Aging Enhances Neural Activity in Auditory, Visual, and Somatosensory Cortices: The Common Cause Revisited.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Visual cortical responses in age-related hearing loss show evidence for compensatory neuroplasticity.GeroScience · 2026Article
- Enhanced Contour-Deviant Mismatch Negativity and Mnemonic Representations in Older Musicians.The European journal of neuroscience · 2026Article
- Early Signs of Aging in Auditory Function Reflected in the Event-Related Potentials.Journal of the American Academy of Audiology · 2026Article
- Functional Dissociation of Mismatch Negativity From Late Discriminative Negativity Across the Adult Lifespan.The European journal of neuroscience · 2026Article
- Neural features underlying high-accuracy classification of amnestic mild cognitive impairment using multi-sensory-evoked potentials.GeroScience · 2026Article
- Neuro-cortical signatures of attention in uni- and multi-sensory audio-visual processing in children.Neuroscience · 2026Article
- Somatosensory and visual evoked potentials and brainstem auditory evoked responses in osteoarthritic cats with chronic pain - a comparative study.Frontiers in veterinary science · 2026Article
- Age-related auditory nerve deficits propagate central gain throughout the auditory system: Associations with cortical microstructure and speech recognition.Neurobiology of aging · 2026Article
- ERP Biomarkers of Auditory-Visual Distraction in Aging and Cognitive Impairment.Brain sciences · 2025Article
- Chronic alcohol-induced brain states limit propagation of direct cortical stimulation.Scientific reports · 2025Article
- Effect of Dual-task Standing on prefrontal-motor Cortex Activation and postural-related Muscle Activity between Young and Older Adults.Brain topography · 2025Article
- CaMK modulates sensory neural activity to control longevity and proteostasis.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Effects of age on the neural correlates of auditory working memory in cochlear implant users.PloS one · 2025Article
- Cross-modal neuroplasticity in partial hearing loss: a mini-review.Frontiers in neuroscience · 2025Review
- Interconnected declines in audition vision and cognition in healthy aging.Scientific reports · 2024Article
- Temporal and Fronto-Central Auditory Evoked Responses in Children with Neurodevelopmental Disorders: A Scoping Review.NeuroSci · 2024Article
- Age-associated changes in multimodal pain perception.Age and ageing · 2024Article
- Neural correlates underlying local and global processing during visual search across adulthood.PloS one · 2024Article
- Age and sex effects on paired-pulse suppression and prepulse inhibition of auditory evoked potentials.Frontiers in neuroscience · 2024Article
- BOLD fMRI responses to amplitude-modulated sounds across age in adult listeners.Imaging neuroscience (Cambridge, Mass.) · 2024Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In humans, age-related declines in vision, hearing, and touch coincide with changes in amplitude and latency of sensory-evoked potentials. These age-related differences in neural activity may be related to a common deterioration of supra-modal brain areas (e.g., PFC) that mediate activity in sensory cortices or reflect specific sensorineural impairments that may differ between sensory modalities. To distinguish between these two possibilities, we measured neuroelectric brain activity while 37 young adults (18-30 years, 18 males) and 35 older adults (60-88 years, 20 males) were presented with a rapid randomized sequence of lateralized auditory, visual, and somatosensory stimuli. Within each sensory domain, we compared amplitudes and latencies of sensory-evoked responses, source activity, and functional connectivity (via phase-locking value) between groups. We found that older adults' early sensory-evoked responses were greater in amplitude than those of young adults in all three modalities, which coincided with enhanced source activity in auditory, visual, and somatosensory cortices. Older adults also showed stronger neural synchrony than young adults between superior prefrontal and sensory cortices; and in older adults, the degree of phase synchrony was positively correlated with the magnitude of source activity in sensory areas. Critically, older adults who showed enhanced neural activity in one sensory domain also showed enhanced activity in other modalities. Together, these findings support the common cause hypothesis of aging and highlight the role of prefrontal regions in exerting top-down control over sensory cortices.
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