Evidence map›Paper›PMID 34772729›Full record

ArticleClinical journal of the American Society of Nephrology : CJASN2022

Nocturnal Dipping and Left Ventricular Mass Index in the Chronic Kidney Disease in Children Cohort.

Christine Y Bakhoum, Ronit Katz, Joshua A Samuels, Tala Al-Rousan, Susan L Furth, Joachim H Ix, Pranav S Garimella

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Clinical journal of the American Society of Nephrology : CJASN, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00327860 (Chronic Kidney Disease in Children Prospective Cohort Study), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00327860 recruitingnot on this map

Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)

TypeobservationalSponsorJohns Hopkins Bloomberg School of Public HealthRan2003 to 2028Enrolled1,300ConditionsChronic Kidney Disease
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Predictors of daytime blood pressure, nighttime blood pressure, and nocturnal dipping in patients with chronic kidney disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Christine Y BakhoumDepartment of Pediatrics, Section of Pediatric Nephrology, Yale University, New Haven, Connecticut.ORCID 0000-0002-7077-5472
Ronit KatzDepartment of Obstetrics and Gynecology, University of Washington, Seattle, Washington.
Joshua A SamuelsDivision of Pediatric Nephrology & Hypertension, McGovern Medical School at the University of Texas Health Science Center, Houston, Texas.
Tala Al-RousanDivision of Global Public Health, Department of Medicine, University of California San Diego, La Jolla, California.
Susan L FurthDepartment of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Joachim H IxDivision of Nephrology and Hypertension, Department of Medicine, University of California San Diego, La Jolla, California.
Pranav S GarimellaDivision of Nephrology and Hypertension, Department of Medicine, University of California San Diego, La Jolla, California.ORCID 0000-0002-6016-4715
University of California San Diego · USChildren's Hospital of Philadelphia · USThe University of Texas Health Science Center at Houston · USUniversity of Washington · USYale University · US

Funding

Chronic Kidney Disease in Children Study (C-Kid)U01DK066174 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SUSAN L. FURTH · 2003 to 2026
$25.1M
CKiD Cardiovascular Testing Travel SupplementU01DK066143 · NIDDK · CHILDREN'S MERCY HOSP (KANSAS CITY, MO) · PI Bradley Alan Warady · 2003 to 2026
$24.2M
The Kidney Disease in Children Data Management and Analysis Center (KIDMAC)U24DK066116 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI Derek K Ng · 2018 to 2026
$12.6M
Central Biochemistry Laboratory of the CKID ConsortiumU24DK082194 · NIDDK · UNIVERSITY OF ROCHESTER · PI SCHWARTZ, GEORGE J · 2018 to 2022
$1.7M
Blood Pressure Control Advancing Refugee Health Equity (BPCARE): an RCT of adherenceR01HL173155 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Tala Al-Rousan · 2025 to 2026
$1.3M
Adult and Pediatric Nephrology Clinical Investigation Training ProgramT32DK104717 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI IX, JOACHIM H · 2016 to 2020
$1.3M
Tubular secretion, kidney disease progression, and drug dosing in older adultsK23DK114556 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GARIMELLA, PRANAV · 2018 to 2022
$1.0M
Hypertension Self-management in Refugees Living in San DiegoK23HL148530 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AL-ROUSAN, TALA · 2020 to 2024
$882k
Mentored Patient Oriented Research in Kidney DiseaseK24DK110427 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI IX, JOACHIM H · 2016 to 2020
$780k
NHLBI NIH HHS K23 HL148530NHLBI NIH HHS R01 HL173155NIDDK NIH HHS K23 DK114556NIDDK NIH HHS K24 DK110427NIDDK NIH HHS T32 DK104717NIDDK NIH HHS U01 DK066143NIDDK NIH HHS U01 DK066174NIDDK NIH HHS U24 DK066116NIDDK NIH HHS U24 DK082194
6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe physiologic nocturnal BP decline is often blunted in patients with CKD; however, the consequences of BP nondipping in children are largely unknown. Our objective was to determine risk factors for nondipping and to investigate if nondipping is associated with higher left ventricular mass index in children with CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted a cross-sectional analysis of ambulatory BP monitoring and echocardiographic data in participants of the Chronic Kidney Disease in Children study. Multivariable linear and spline regression analyses were used to evaluate the relationship of risk factors with dipping and of dipping with left ventricular mass index.

resultsWithin 552 participants, mean age was 11 (±4) years, mean eGFR was 53 (±20) ml/min per 1.73 m

conclusionsBlack race, female sex, and greater proteinuria and sodium intake were significantly associated with blunted dipping in children with CKD. We did not find a statistically significant association between dipping and left ventricular mass index. PODCAST: This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2021_12_20_CJN09810721.mp3.

Indexed as

Blood Pressure Monitoring, AmbulatoryAdolescentChildCohort StudiesCross-Sectional StudiesFemaleHeart VentriclesHumansMaleOrgan SizeRenal Insufficiency, ChronicRisk Factorsambulatory blood pressureblood pressurechronic kidney diseaseclinical epidemiologycohort studiesnondippingpediatrics

Identifiers

PMID34772729
PMCPMC8763165
OpenAlexW3214089163

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.