Evidence map›Paper›PMID 34772584›Full record

ArticleJournal of Ayurveda and integrative medicine

Physico-chemical characterization of kajjali, black sulphide of mercury, with respect to the role of sulfur in its formation and structure.

Namrata Joshi, Manoj Kumar Dash, Chandan Upadhyay, Vikas Jindal, Pradip Kumar Panda, Manjari Shukla

Open access · goldAbstract read
In one paragraph

Article in Journal of Ayurveda and integrative medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Namrata JoshiDept. of Rasashastra, Faculty of Ayurveda, IMS, Banaras Hindu University, Varanasi, 221005, India.
Manoj Kumar DashDept. of Rasashastra, Govt. Ayurveda College, Raipur, C.G, India. Electronic address: drmanojkumardash@gmail.com.
Chandan UpadhyayMaterials Science and Technology, School of Materials Science and Technology, Indian Institute of Technology, Banaras Hindu University, Varanasi, 221005, India.
Vikas JindalDepartment of Metallurgical Engineering, Indian Institute of Technology (BHU), Varanasi, 221005, India.
Pradip Kumar PandaGovt. Ayurveda College, Balangir, Odisha, India.
Manjari ShuklaMaterials Science and Technology, School of Materials Science and Technology, Indian Institute of Technology, Banaras Hindu University, Varanasi, 221005, India.
Banaras Hindu University · INVaidyaratnam P.S. Varier Ayurveda College · INIndian Institute of Technology BHU · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKajjali is used as a base for Ayurvedic herbo-mineral medicines. It is a combination of mercury with sulfur in varying proportions. The ratio of sulfur (S) added to mercury (Hg) directly relates to the therapeutic efficacy of the compound.

objectiveTo analyze the physico-chemical characteristics of samaguna gandhaka kajjali (Hg: S = 1:1) and shadaguna gandhaka kajjali (Hg: S = 1:6). MATERIALS AND

methodsX-ray diffraction, scanning electron microscopy, X-ray photoelectron spectroscopy (XPS), Fourier transmission infrared spectroscopy, thermo-gravimetry analysis, and atomic absorption spectroscopy were applied to characterize each type of kajjali.

resultsIt was found that the particle size of the formed kajjali compound increases with a decrease in the mercury to sulfur ratio. The presence of excess sulfur does not change the surface oxidation states as revealed by the XPS analysis. No trace of mercury has been found in both samaguna gandhaka kajjali (SGK-1) and shadguna gandhaka kajjali (SGK-6), indicating a complete Hg reaction with S.

conclusionKajjali simulates nanomaterial of the modern era and possesses therapeutic efficacy as mentioned in classical Ayurveda texts. Complete trituration of mercury and sulfur combination ends up with this kajjali formation incorporating the potency of nanotherapeutics.

Indexed as

AyurvedaBlack sulfideKajjaliNanoparticleSafetySulfur ratio

Identifiers

PMID34772584
PMCPMC8642700
OpenAlexW3212633788

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.