ArticleBMC psychiatry2021
Validity of the patient health questionnaire 9-item in autistic youths: a pilot study.
Article in BMC psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- A systematic review and meta-analysis of suicidality in autistic and possibly autistic people without co-occurring intellectual disability.Molecular autism · 2023Pooled it
- Effect of high-frequency stellate ganglion block on sleep and affective symptoms in insomnia disorder: a prospective pilot study.BMC neurology · 2026Trial
- A systematic review of existing brief interventions for youth following suicide attempt: informing the development of an autism-adapted intervention.Frontiers in psychiatry · 2026Review
- Measurement of Anxiety and Depression Among Autistic Adults: Concordance Between Diagnostic and Screening Instruments in a Feasibility Study.Journal of autism and developmental disorders · 2025Article
- Psychometric Properties of Measuring Tools for Depression in Autistic Youths: A Systematic Review.Journal of autism and developmental disorders · 2025Article
- Retrospective Rates of Positive Depression Screens in Pediatric Diabetes Using Two PHQ-9 Cutoff Scores: A Brief Report.Clinical practice in pediatric psychology · 2025Article
- Poor performance of PHQ-9 and GAD-7 in screening clinical depression and anxiety among a large sample of Chinese children and adolescents.BMC psychiatry · 2025Article
- Suicidal Thoughts and Behaviors in People on the Autism Spectrum.Current psychiatry reports · 2024Review
- Autistic traits in adolescents in psychiatric inpatient care: Clinical and demographic characteristics and correlates.Research in autism spectrum disorders · 2024Article
- The importance of social relationships in depression in autistic adolescents: a narrative-review.Frontiers in psychology · 2024Review
- Mixed experiences with online learning among neurodiverse youth: Evidence from video recordings of a longitudinal study.PLOS mental health · 2024Article
- Mental health challenges faced by autistic people.Nature human behaviour · 2023Review
- Psychometric properties of the revised children's anxiety and depression scale (RCADS) for autistic youth without co-occurring intellectual disability.Journal of mood and anxiety disorders · 2023Article
- The correlation between OSA-related quality of life and two mental statuses in adolescent Chinese patients with cleft palate: A comprehensive study.Frontiers in pediatrics · 2022Article
- Lower Completion of Depression Screening and Higher Positivity Among Autistic Adolescents Across a Large Pediatric Primary Care Network.Academic pediatricsArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAutistic adolescents have greater predisposition to depression and suicidality than neurotypical adolescents. Early detection is essential for timely treatment. The Patient Health Questionnaire 9-item (PHQ-9) is a brief screen for depression. The study examines the validity of the PHQ-9 for detecting major depressive disorder (MDD) in autistic youths.
methodsEnglish speaking youths aged 10-18 years, with DSM-IV/DSM-5/ICD-10 diagnosis of Autism Spectrum Disorder (ASD), and their parents presenting to a child psychiatric service were invited to participate between May 2018 to August 2020. Participants completed the respective self- and parent-rated PHQ-9 independently. MDD was verified using the MINI-Kid (Mini-International Neuropsychiatric Interview, Kid version).
resultsOne hundred one youth, mean (SD) age 14.6 (2.3), were enrolled. 27 (27%) met criteria for current MDD. Mean total PHQ-9 scores, percentage ratings for severity of symptoms of depression, functional impairment, dysthymia and suicidality were compared. Areas under the ROC curve and statistically optimal cutoffs were determined. Parents rated depressive symptoms severity lower than their children. The PHQ-9 displayed low sensitivity with high false negative rates at conventional, adjusted and proposed cutoffs.
conclusionsFuture studies should improve on the validity and reliability of existing depression screening tools, or develop more appropriate screening methods of depression, for autistic youths.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.