Evidence map›Paper›PMID 34771995›Full record

ArticleMaterials (Basel, Switzerland)2021

Effective and Selective Extraction of Quercetin from Onion (

Matteo Ciardi, Federica Ianni, Roccaldo Sardella, Stefano Di Bona, Lina Cossignani, Raimondo Germani, Matteo Tiecco, Catia Clementi

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Pharmaceutics · 2026
    Article
  3. Onion (Food science & nutrition · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Water-Induced Restructuring of the Surface of a Deep Eutectic Solvent.The journal of physical chemistry letters · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Matteo CiardiDepartment of Chemistry, Biology and Biotecnology, University of Perugia, Via Elce di Sotto 8, 06123 Perugia, Italy.
Federica IanniDepartment of Pharmaceutical Sciences, University of Perugia, Via Fabretti 48, 06123 Perugia, Italy.ORCID 0000-0003-4293-3100
Roccaldo SardellaDepartment of Pharmaceutical Sciences, University of Perugia, Via Fabretti 48, 06123 Perugia, Italy.ORCID 0000-0001-9856-0230
Stefano Di BonaDepartment of Chemistry, Biology and Biotecnology, University of Perugia, Via Elce di Sotto 8, 06123 Perugia, Italy.
Lina CossignaniDepartment of Pharmaceutical Sciences, University of Perugia, Via Fabretti 48, 06123 Perugia, Italy.ORCID 0000-0003-3433-604X
Raimondo GermaniDepartment of Chemistry, Biology and Biotecnology, University of Perugia, Via Elce di Sotto 8, 06123 Perugia, Italy.ORCID 0000-0001-7076-7475
Matteo TieccoDepartment of Chemistry, Biology and Biotecnology, University of Perugia, Via Elce di Sotto 8, 06123 Perugia, Italy.
Catia ClementiDepartment of Chemistry, Biology and Biotecnology, University of Perugia, Via Elce di Sotto 8, 06123 Perugia, Italy.
University of Perugia · IT

Funding

Fondazione Cassa di Risparmio di Perugia Grant number 220.0513
6 · The paper itself

Abstract

Deep Eutectic Solvents (DESs) are experiencing growing interest as substitutes of polluting organic solvents for their low or absent toxicity and volatility. Moreover, they can be formed with natural bioavailable and biodegradable molecules; they are synthesized in absence of hazardous solvents. DESs are, inter alia, successfully used for the extraction/preconcentration of biofunctional molecules from complex vegetal matrices. Onion skin is a highly abundant waste material which represents a reservoir of molecules endowed with valuable biological properties such as quercetin and its glycosylated forms. An efficient extraction of these molecules from dry onion skin from "Dorata di Parma" cultivar was obtained with water dilution of acid-based DESs. Glycolic acid (with betaine 2/1 molar ratio and L-Proline 3/1 molar ratio as counterparts) and of

Indexed as

Deep Eutectic SolventsDESs water dilutionsextractionpreconcentrationquercetinrecoveryRP-HPLC-UVUHPLC-MS/MS

Identifiers

PMID34771995
PMCPMC8585411
OpenAlexW3208483336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.