Evidence map›Paper›PMID 34771676›Full record

ArticleCancers2021

Enhancing the Therapeutic Effect of 2-

Hirofumi Hanaoka, Yasuhiro Ohshima, Hiroyuki Suzuki, Ichiro Sasaki, Tadashi Watabe, Kazuhiro Ooe, Shigeki Watanabe, Noriko S Ishioka

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Hirofumi HanaokaFaculty of Medicine, Kansai Medical University, 2-5-1 Shin-machi, Hirakata 573-1010, Osaka, Japan.
Yasuhiro OhshimaDepartment of Radiation-Applied Biology Research, Quantum Beam Science Research Directorate, National Institute for Quantum Science and Technology, 1233 Watanuki-machi, Takasaki 370-1292, Gunma, Japan.
Hiroyuki SuzukiDepartment of Molecular Imaging and Radiotherapy, Graduate School of Pharmaceutical Science, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8675, Chiba, Japan.ORCID 0000-0002-9560-4274
Ichiro SasakiDepartment of Radiation-Applied Biology Research, Quantum Beam Science Research Directorate, National Institute for Quantum Science and Technology, 1233 Watanuki-machi, Takasaki 370-1292, Gunma, Japan.
Tadashi WatabeDepartment of Nuclear Medicine and Tracer Kinetics, Graduate School of Medicine, Osaka University, 1-1 Yamadaoka, Suita 565-0871, Osaka, Japan.ORCID 0000-0001-8658-2395
Kazuhiro OoeDepartment of Nuclear Medicine and Tracer Kinetics, Graduate School of Medicine, Osaka University, 1-1 Yamadaoka, Suita 565-0871, Osaka, Japan.
Shigeki WatanabeDepartment of Radiation-Applied Biology Research, Quantum Beam Science Research Directorate, National Institute for Quantum Science and Technology, 1233 Watanuki-machi, Takasaki 370-1292, Gunma, Japan.ORCID 0000-0002-8556-8580
Noriko S IshiokaDepartment of Radiation-Applied Biology Research, Quantum Beam Science Research Directorate, National Institute for Quantum Science and Technology, 1233 Watanuki-machi, Takasaki 370-1292, Gunma, Japan.
National Institutes for Quantum Science and Technology · JPThe University of Osaka · JPChiba University · JPKansai Medical University · JP

Funding

Japan Society for the Promotion of Science 18H02760 and 21H02871
6 · The paper itself

Abstract

L-type amino acid transporter 1 (LAT1) might be a useful target for tumor therapy since it is highly expressed in various types of cancers. We previously developed an astatine-211 (

Indexed as

2-211At-astato-α-methyl-L-phenylalanineblood clearanceprobenecidtargeted alpha therapytumor retention

Identifiers

PMID34771676
PMCPMC8583516
OpenAlexW3209199757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.