Evidence map›Paper›PMID 34771651›Full record

ArticleCancers2021

In Vivo Reflectance Confocal Microscopy as a Response Monitoring Tool for Actinic Keratoses Undergoing Cryotherapy and Photodynamic Therapy.

Clara Curiel-Lewandrowski, Caitlyn N Myrdal, Kathylynn Saboda, Chengcheng Hu, Edith Arzberger, Giovanni Pellacani, Franz Josef Legat, Martina Ulrich, Petra Hochfellner, Margaret C Oliviero and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Clinical and Dermoscopic Diagnosis of Actinic Keratosis.Dermatology practical & conceptual · 2024
    Review
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  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Clara Curiel-LewandrowskiDivision of Dermatology, The University of Arizona College of Medicine, Tucson, AZ 85724, USA.
Caitlyn N MyrdalDivision of Dermatology, The University of Arizona College of Medicine, Tucson, AZ 85724, USA.ORCID 0000-0002-5723-5535
Kathylynn SabodaThe University of Arizona Cancer Center, Tucson, AZ 85724, USA.
Chengcheng HuDepartment of Epidemiology and Biostatistics, Mel and Zuckerman College of Public Health, The University of Arizona, Tucson, AZ 85721, USA.
Edith ArzbergerDepartment of Dermatology, Medical University of Graz, 8036 Graz, Austria.
Giovanni PellacaniDermatology, Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, La Sapienza University of Rome, 00185 Rome, Italy.
Franz Josef LegatDepartment of Dermatology, Medical University of Graz, 8036 Graz, Austria.
Martina UlrichCMB Collegium Medicum Berlin GmbH/Dermatology Office, 10117 Berlin, Germany.
Petra HochfellnerDepartment of Dermatology, Medical University of Graz, 8036 Graz, Austria.
Margaret C OlivieroSkin and Cancer Associates, Fort Lauderdale, FL 33324, USA.
Paola PasqualiPius Hospital of Valls, 43850 Tarragona, Spain.ORCID 0000-0003-1504-0665
Melissa GillFaculty of Medicine and Health Sciences, University of Alcalá de Henares, 28801 Madrid, Spain.ORCID 0000-0002-2413-1916
Rainer Hofmann-WellenhofDepartment of Dermatology, Medical University of Graz, 8036 Graz, Austria.
Medical University of Graz · ATUniversity of Arizona · USSapienza University of Rome · ITSkin Cancer Foundation · USSUNY Downstate Health Sciences University · USUniversidad de Alcalá · ES

Funding

Targeted Prevention for Non-Melanoma Skin CancerP01CA229112 · NCI · UNIVERSITY OF ARIZONA · PI MANSOUR, HEIDI M. · 2019 to 2023
$7.1M
NCI NIH HHS P01 CA229112Targeted Prevention for Non-Melanoma Skin Cancer PO1 Grant CA27502, NCI/NIHThe Alan and Janice Levin Family Endowed Chair for Excellence in Cancer Research at the Arizona Cancer Center N/A
6 · The paper itself

Abstract

Reflectance confocal microscopy (RCM) presents a non-invasive method to image actinic keratosis (AK) at a cellular level. However, RCM criteria for AK response monitoring vary across studies and a universal, standardized approach is lacking. We aimed to identify reliable AK response criteria and to compare the clinical and RCM evaluation of responses across AK severity grades. Twenty patients were included and randomized to receive either cryotherapy (

Indexed as

actinic keratosiscryotherapyphotodynamic therapyRCMreflectance confocal microscopyresponse monitoring

Identifiers

PMID34771651
PMCPMC8583298
OpenAlexW3211164395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.