Evidence map›Paper›PMID 34771630›Full record

ArticleCancers2021

Genomic Instability of Circulating Tumor DNA as a Prognostic Marker for Pancreatic Cancer Survival: A Prospective Cohort Study.

Sang Myung Woo, Min Kyeong Kim, Boram Park, Eun-Hae Cho, Tae-Rim Lee, Chang-Seok Ki, Kyong-Ah Yoon, Yun-Hee Kim, Wonyoung Choi, Do Yei Kim and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Sang Myung WooCenter for Liver and Pancreatobiliary Cancer, National Cancer Center, Goyang 10408, Korea.ORCID 0000-0003-3786-4403
Min Kyeong KimDivision of Translational Science, National Cancer Center, Goyang 10408, Korea.
Boram ParkBiostatistics Collaboration Team, Research Core Center, Research Institute, National Cancer Center, Goyang 10408, Korea.
Eun-Hae ChoGenome Research Center, GC Genome, Yongin 16924, Korea.
Tae-Rim LeeGenome Research Center, GC Genome, Yongin 16924, Korea.ORCID 0000-0003-0684-6552
Chang-Seok KiGenome Research Center, GC Genome, Yongin 16924, Korea.
Kyong-Ah YoonCollege of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.ORCID 0000-0002-9823-7393
Yun-Hee KimCancer Biomedical Science, National Cancer Center Graduate School of Cancer Science and Policy, Goyang 10408, Korea.ORCID 0000-0001-7571-9958
Wonyoung ChoiCancer Biomedical Science, National Cancer Center Graduate School of Cancer Science and Policy, Goyang 10408, Korea.
Do Yei KimGenome Research Center, GC Genome, Yongin 16924, Korea.
Jin-Hyeok HwangDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Korea.
Jae Hee ChoDepartment of Internal Medicine, Gachon University Gil Medical Center, Incheon 21556, Korea.ORCID 0000-0003-4174-0091
Sung-Sik HanCenter for Liver and Pancreatobiliary Cancer, National Cancer Center, Goyang 10408, Korea.
Woo Jin LeeCenter for Liver and Pancreatobiliary Cancer, National Cancer Center, Goyang 10408, Korea.
Sang-Jae ParkCenter for Liver and Pancreatobiliary Cancer, National Cancer Center, Goyang 10408, Korea.
Sun-Young KongCancer Biomedical Science, National Cancer Center Graduate School of Cancer Science and Policy, Goyang 10408, Korea.ORCID 0000-0003-0620-4058
National Cancer Center · KRGenome and Company (South Korea) · KRKonkuk University · KRSeoul National University Bundang Hospital · KRYonsei University · KR

Funding

Korea Health Industry Development Institute HI19C0176
6 · The paper itself

Abstract

Genomic instability of circulating tumor DNA (ctDNA) as a prognostic biomarker has not been evaluated in pancreatic cancer. We investigated the role of the genomic instability index of ctDNA in pancreatic ductal adenocarcinoma (PDAC). We prospectively enrolled 315 patients newly diagnosed with resectable (

Indexed as

circulating tumor DNAgenomic instabilitygenomic instability indexinstability scoreoutcome predictionpancreatic cancerpancreatic ductal adenocarcinomaprognostic biomarker

Identifiers

PMID34771630
PMCPMC8582446
OpenAlexW3210875539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.