Evidence map›Paper›PMID 34771583›Full record

ArticleCancers2021

Lack of Benefit of Extending Temozolomide Treatment in Patients with High Vascular Glioblastoma with Methylated

María Del Mar Álvarez-Torres, Elies Fuster-García, Carmen Balaña, Josep Puig, Juan M García-Gómez

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

María Del Mar Álvarez-TorresBiomedical Data Science Laboratory, Instituto Universitario de Tecnologías de la Información y Comunicaciones, Universitat Politècnica de València, 46022 Valencia, Spain.
Elies Fuster-GarcíaBiomedical Data Science Laboratory, Instituto Universitario de Tecnologías de la Información y Comunicaciones, Universitat Politècnica de València, 46022 Valencia, Spain.ORCID 0000-0002-0716-8960
Carmen BalañaInstitut Catala d'Oncologia (ICO), Applied Research Group in Oncology (B-ARGO Group), Institut Investigació Germans Trias i Pujol (IGTP), 08916 Badalona, Spain.
Josep PuigInstitut de Diagnostic per la Image (IDI), Hospital Dr. Josep Trueta, 17007 Girona, Spain.
Juan M García-GómezBiomedical Data Science Laboratory, Instituto Universitario de Tecnologías de la Información y Comunicaciones, Universitat Politècnica de València, 46022 Valencia, Spain.ORCID 0000-0002-3851-1557
Universitat Politècnica de València · ESInstitut Català d'Oncologia · ESOslo University Hospital · NO

Funding

Fundació La Marató TV3 665/C/2013H2020-SC1-2016-CNECT Project (No. 727560)H2020-SC1-BHC-2018-2020 (No. 825750)Marie Skłodowska-Curie grant agreement No 844646National Plan for Scientific and Technical Research and Innovation 2017-2020 No. PID2019-104978RB-I00Programa Estatal de Promoción del Talento y su Empleabilidad en I+D+i DPI2016-80054-RSouth-Eastern Norway Regional Health Authority Grant 2021057
6 · The paper itself

Abstract

In this study, we evaluated the benefit on survival of the combination of methylation of O6-methylguanine-DNA methyltransferase (

Indexed as

adjuvant temozolomidechemotherapyglioblastomaMGMT methylationMRI perfusionpersonalized medicinerCBVsurvivaltemozolomide cyclestumor vascularity

Identifiers

PMID34771583
PMCPMC8582449
OpenAlexW3210834898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.