Evidence map›Paper›PMID 34771579›Full record

ReviewCancers2021

Clinical, Pathological, and Molecular Features of Breast Carcinoma Cutaneous Metastasis.

Silvia González-Martínez, David Pizarro, Belén Pérez-Mies, Tamara Caniego-Casas, Giuseppe Curigliano, Javier Cortés, José Palacios

Abstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. A Case Report of Zosteriform Cutaneous Metastases from Breast Carcinoma.Clinical, cosmetic and investigational dermatology · 2024
    Article
  11. Topical Calcipotriol Plus Imiquimod Immunotherapy for Nonkeratinocyte Skin Cancers.JID innovations : skin science from molecules to population health · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Silvia González-MartínezClinical Researcher, Hospital Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0002-8139-8369
David PizarroDepartment of Pathology, Hospital Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0002-8945-9541
Belén Pérez-MiesDepartment of Pathology, Hospital Ramón y Cajal, 28034 Madrid, Spain.
Tamara Caniego-CasasDepartment of Pathology, Hospital Ramón y Cajal, 28034 Madrid, Spain.
Giuseppe CuriglianoEuropean Institute of Oncology, IRCCS, 20141 Milan, Italy.ORCID 0000-0003-1781-2518
Javier CortésCIBER-ONC, Instituto de Salud Carlos III, 28029 Madrid, Spain.ORCID 0000-0001-7623-1583
José PalaciosDepartment of Pathology, Hospital Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0002-6730-5066

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous metastases (CMs) account for 2% of all skin malignancies, and nearly 70% of CMs in women originate from breast cancer (BC). CMs are usually associated with poor prognosis, are difficult to treat, and can pose diagnostic problems, such as in histopathological diagnosis when occurring long after development of the primary tumor. In addition, the molecular differences between the primary tumors and their CMs, and between CMs and metastases in other organs, are not well defined. Here, we review the main clinical, pathological, and molecular characteristics of breast cancer CMs. Identifying molecular markers in primary BC that predict CM and can be used to determine the molecular differences between primary tumors and their metastases is of great interest for the design of new therapeutic approaches.

Indexed as

breast cancerCNVimmunohistochemistrymetastasismutationpathologyskin

Identifiers

PMID34771579
PMCPMC8582578

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.