Evidence map›Paper›PMID 34771572›Full record

ArticleCancers2021

Maternal Thyroid Disease and the Risk of Childhood Cancer in the Offspring.

Laura K Seppälä, Laura-Maria Madanat-Harjuoja, Maarit K Leinonen, Mitja Lääperi, Kim Vettenranta

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
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  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Laura K SeppäläPediatrics, Helsinki University Hospital, 00290 Helsinki, Finland.ORCID 0000-0003-3028-9127
Laura-Maria Madanat-HarjuojaInstitute for Statistical and Epidemiological Research, Finnish Cancer Registry, 00130 Helsinki, Finland.
Maarit K LeinonenData and Analytics Unit, Information Services Department, Finnish Institute for Health and Welfare, 00271 Helsinki, Finland.ORCID 0000-0002-7631-4749
Mitja LääperiPediatric Research Center, Children's Hospital, Helsinki University Hospital, 00290 Helsinki, Finland.
Kim VettenrantaPediatrics, Helsinki University Hospital, 00290 Helsinki, Finland.
University of Helsinki · FIFinnish Cancer Registry · FIFinnish Institute for Health and Welfare · FIHelsinki University Hospital · FI

Funding

Children's Cancer Foundation Aamu No numberLastentautien Tutkimussäätiö No numberVäre Foundation for Pediatric Cancer Research No number
6 · The paper itself

Abstract

Maternal thyroid disease, especially hypothyroidism, affects pregnancy and its outcome. In-utero exposure to autoimmune thyroid disease has been reported to associate with childhood ALL in the offspring. We evaluated the risk of childhood cancer in the offspring following exposure to maternal thyroid disease in a case-control setting using registry data. All patients with their first cancer diagnosis below the age of 20 years were identified from the Finnish Cancer Registry (

Indexed as

adolescent cancercancer riskcase-controlchildhood cancermaternal thyroid diseaseregistry-basedthyroid hormone

Identifiers

PMID34771572
PMCPMC8582383
OpenAlexW3209459901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.