Evidence map›Paper›PMID 34771559›Full record

ArticleCancers2021

Ramya Thota, Mingli Yang, Lance Pflieger, Michael J Schell, Malini Rajan, Thomas B Davis, Heiman Wang, Angela Presson, Warren Jack Pledger, Timothy J Yeatman

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Ramya ThotaOncology Clinical Program, Intermountain Healthcare, Murray, UT 84107, USA.
Mingli YangDepartment of Surgery, University of Utah, Salt Lake City, UT 84132, USA.
Lance PfliegerPrecision Genomics Translational Science Center, Intermountain Healthcare, Murray, UT 84107, USA.
Michael J SchellDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.
Malini RajanDepartment of Surgery, University of Utah, Salt Lake City, UT 84132, USA.
Thomas B DavisDepartment of Surgery, University of Utah, Salt Lake City, UT 84132, USA.
Heiman WangDepartment of Surgery, University of Utah, Salt Lake City, UT 84132, USA.
Angela PressonDepartment of Internal Medicine, Division of Epidemiology, University of Utah, Salt Lake City, UT 84132, USA.
Warren Jack PledgerDepartment of Surgery, University of Utah, Salt Lake City, UT 84132, USA.
Timothy J YeatmanDepartment of Surgery, University of Utah, Salt Lake City, UT 84132, USA.
University of Utah · USIntermountain Healthcare · USHuntsman Cancer Institute · USMoffitt Cancer Center · US

Funding

CLINCIAL VALIDATION OF APC AND TP53 AS BIOMARKERS FOR CETUXIMAB RESPONSEUH3CA227955 · NCI · UNIVERSITY OF UTAH · PI YEATMAN, TIMOTHY J · 2021 to 2023
$917k
NCI NIH HHS UH3 CA227955NIH HHS UH3CA227955
6 · The paper itself

Abstract

Recently, it was suggested that consensus molecular subtyping (CMS) may aide in predicting response to EGFR inhibitor (cetuximab) therapies. We recently identified that

Indexed as

APCcetuximabCMS classificationcolorectal cancerEGFR inhibitorsmutationsTP53

Identifiers

PMID34771559
PMCPMC8582550
OpenAlexW3209858902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.