Evidence map›Paper›PMID 34771543›Full record

ArticleCancers2021

How the Severity and Mechanism of Recurrent Laryngeal Nerve Dysfunction during Monitored Thyroidectomy Impact on Postoperative Voice.

Tzu-Yen Huang, Wing-Hei Viola Yu, Feng-Yu Chiang, Che-Wei Wu, Shih-Chen Fu, An-Shun Tai, Yi-Chu Lin, Hsin-Yi Tseng, Ka-Wo Lee, Sheng-Hsuan Lin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Balancing hemostasis and function: the impact of hemostatic materials on voice and swallowing outcomes in nerve-preserved thyroidectomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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  12. The INMSG Survey on the Loss of Signal Management on the First Side During Planned Bilateral Thyroid Surgery.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Tzu-Yen HuangInternational Thyroid Surgery Center, Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0002-5044-0325
Wing-Hei Viola YuInternational Thyroid Surgery Center, Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Feng-Yu ChiangDepartment of Otolaryngology-Head and Neck Surgery, E-Da Hospital, Kaohsiung 824, Taiwan.
Che-Wei WuInternational Thyroid Surgery Center, Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0003-1052-5348
Shih-Chen FuInstitute of Statistics, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.
An-Shun TaiInstitute of Statistics, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.
Yi-Chu LinInternational Thyroid Surgery Center, Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Hsin-Yi TsengInternational Thyroid Surgery Center, Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Ka-Wo LeeInternational Thyroid Surgery Center, Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Sheng-Hsuan LinInstitute of Statistics, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.ORCID 0000-0003-0714-2354
Kaohsiung Medical University · TWNational Yang Ming Chiao Tung University · TWE-Da Hospital · TW

Funding

Kaohsiung Medical University Hospital, Kaohsiung Medical University KMUH109-9M44Kaohsiung Municipal Siaogang Hospital/Kaohsiung Medical University Research Center grants KMHK-DK(C)110009, I-109-04, H-109-05, I-108-02Ministry of Science and Technology, Taiwan MOST 108-2628-B-037-006, MOST 109-2628-B-037-014, MOST 110-2636-B-009-008, MOST 110-2314-B-037-104-MY2, MOST 110-2314-B-037-120
6 · The paper itself

Abstract

Intraoperative neuromonitoring can qualify and quantify RLN function during thyroid surgery. This study investigated how the severity and mechanism of RLN dysfunction during monitored thyroid surgery affected postoperative voice. This retrospective study analyzed 1021 patients that received standardized monitored thyroidectomy. Patients had post-dissection RLN(R2) signal <50%, 50-90% and >90% decrease from pre-dissection RLN(R1) signal were classified into Group A-no/mild, B-moderate, and C-severe RLN dysfunction, respectively. Demographic characteristics, RLN injury mechanisms(mechanical/thermal) and voice analysis parameters were recorded. More patients in the group with higher severity of RLN dysfunction had malignant pathology results (A/B/C = 35%/48%/55%,

Indexed as

index of voice and swallowing handicap of thyroidectomy (IVST)intraoperative neuromonitoring (IONM)postoperative voicerecurrent laryngeal nerve (RLN)severity and mechanism of RLN dysfunction

Identifiers

PMID34771543
PMCPMC8582531
OpenAlexW3209053506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.