Evidence map›Paper›PMID 34771536›Full record

ArticleCancers2021

A Mass Spectrometry Imaging Based Approach for Prognosis Prediction in UICC Stage I/II Colon Cancer.

Benedikt Martin, Juliana P L Gonçalves, Christine Bollwein, Florian Sommer, Gerhard Schenkirsch, Anne Jacob, Armin Seibert, Wilko Weichert, Bruno Märkl, Kristina Schwamborn

Abstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
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  5. Review
  6. Article
  7. Pediatric Crohn's disease diagnosis aidFrontiers in pediatrics · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Benedikt MartinInstitute of Pathology and Molecular Tumor Diagnostics, University Hospital of Augsburg, 86156 Augsburg, Germany.
Juliana P L GonçalvesInstitute of Pathology, School of Medicine, Technical University of Munich, 81675 Munich, Germany.ORCID 0000-0002-6634-9876
Christine BollweinInstitute of Pathology, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
Florian SommerDepartment of Visceral Surgery, University Hospital of Augsburg, 86156 Augsburg, Germany.ORCID 0000-0003-3242-3027
Gerhard SchenkirschCancer Tumor Data Management, Comprehensive Cancer Center, University Hospital of Augsburg, 86156 Augsburg, Germany.
Anne JacobInstitute of Pathology, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
Armin SeibertInstitute of Mathematics, Augsburg University, 86159 Augsburg, Germany.
Wilko WeichertInstitute of Pathology, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
Bruno MärklInstitute of Pathology and Molecular Tumor Diagnostics, University Hospital of Augsburg, 86156 Augsburg, Germany.ORCID 0000-0002-7704-850X
Kristina SchwambornInstitute of Pathology, School of Medicine, Technical University of Munich, 81675 Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, pathological evaluation of stage I/II colon cancer, following the Union Internationale Contre Le Cancer (UICC) guidelines, is insufficient to identify patients that would benefit from adjuvant treatment. In our study, we analyzed tissue samples from 276 patients with colon cancer utilizing mass spectrometry imaging. Two distinct approaches are herein presented for data processing and analysis. In one approach, four different machine learning algorithms were applied to predict the tendency to develop metastasis, which yielded accuracies over 90% for three of the models. In the other approach, 1007

Indexed as

colon cancerMALDImass spectrometry imagingproteomicstumor prognosis

Identifiers

PMID34771536
PMCPMC8582467

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.