Evidence map›Paper›PMID 34771480›Full record

ArticleCancers2021

Radiological Patterns of Uveal Melanoma Liver Metastases in Correlation to Genetic Status.

Serdar Yavuzyigitoglu, Michael C Y Tang, Miguel Jansen, Kaspar W Geul, Roy S Dwarkasing, Jolanda Vaarwater, Wojtek Drabarek, Robert M Verdijk, Dion Paridaens, Nicole C Naus and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Management of liver metastases from uveal melanoma.The British journal of surgery · 2025
    Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Serdar YavuzyigitogluDepartment of Ophthalmology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0001-5915-3798
Michael C Y TangDepartment of Ophthalmology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0002-1104-4418
Miguel JansenDepartment of Ophthalmology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
Kaspar W GeulDepartment of Internal Medicine, Sint Franciscus Gasthuis Rotterdam, 3045 PM Rotterdam, The Netherlands.
Roy S DwarkasingDepartment of Radiology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0002-5553-1947
Jolanda VaarwaterDepartment of Ophthalmology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
Wojtek DrabarekDepartment of Ophthalmology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
Robert M VerdijkDepartment of Pathology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0003-1437-214X
Dion ParidaensDepartment of Ophthalmology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0001-6762-3614
Nicole C NausDepartment of Ophthalmology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
Erwin BrosensDepartment of Clinical Genetics, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0001-8235-4010
Annelies de KleinDepartment of Clinical Genetics, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
Emine KilicDepartment of Ophthalmology, Erasmus Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
Erasmus University Rotterdam · NLRotterdam Eye Hospital · NLSint Franciscus Gasthuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study reports the role played by the mutation status of Uveal Melanoma (UM) in relation to hepatic metastatic patterns as seen on imaging modalities. Radiological images were obtained from 123 patients treated at the Erasmus Medical Center Rotterdam or the Rotterdam Eye Hospital. Radiological images were derived from either computed tomography or magnetic resonance imaging. Hepatic metastatic patterns were classified by counting the number of metastases found in the liver. Miliary metastatic pattern (innumerable small metastases in the entire liver) was analyzed separately. Mutation status was determined in 85 patients. Median disease-free survival (DFS) and survival with metastases differed significantly between each of the metastatic patterns (respectively,

Indexed as

BAP1choroidal melanomaeye melanomaliver metastasesSF3B1uveal melanoma

Identifiers

PMID34771480
PMCPMC8582397
OpenAlexW3209080609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.