Evidence map›Paper›PMID 34771446›Full record

ArticleCancers2021

COVID-19 Presentation and Outcomes among Cancer Patients: A Matched Case-Control Study.

Julien Péron, Tristan Dagonneau, Anne Conrad, Fanny Pineau, Sara Calattini, Gilles Freyer, David Perol, Christophe Sajous, Maël Heiblig

Abstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Experiences of cancer care in COVID-19: A longitudinal qualitative study.European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2022
    Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Julien PéronMedical Oncology Department, Institut de Cancérologie des Hospices Civils de Lyon, 69002 Lyon, France.ORCID 0000-0002-1709-5152
Tristan DagonneauMedical Information Department, Hospices Civils de Lyon, 69002 Lyon, France.
Anne ConradInfectious Diseases Department, Croix-Rousse Hospital, 69004 Lyon, France.
Fanny PineauClinical Research Plateform, Institut de Cancérologie des Hospices Civils de Lyon, 69002 Lyon, France.
Sara CalattiniClinical Research Plateform, Institut de Cancérologie des Hospices Civils de Lyon, 69002 Lyon, France.
Gilles FreyerMedical Oncology Department, Institut de Cancérologie des Hospices Civils de Lyon, 69002 Lyon, France.
David PerolCentre Léon Bérard, 69008 Lyon, France.
Christophe SajousMedical Oncology Department, Institut de Cancérologie des Hospices Civils de Lyon, 69002 Lyon, France.
Maël HeibligFaculté de Médecine et de Maïeutique Lyon-Sud-Charles Mérieux, Université Claude Bernard Lyon 1, 69310 Pierre-Bénite, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been suggested that cancer patients are at higher risk of contracting COVID-19 and at higher risk of developing a severe form of the disease and fatality. This study's objectives were to measure the excess risk of mortality and morbidity of patients with cancer among patients hospitalized for a SARS-CoV-2 infection, and to identify factors associated with the risk of death and morbidity among cancer patients. All first cancer patients hospitalized for COVID-19 in the two main hospitals of the Lyon area were included. These patients were matched based on age, gender, and comorbidities with non-cancer control patients. A total of 108 cancer patients and 193 control patients were included. The severity at admission and the symptoms were similar between the two groups. The risk of early death was higher among cancer patients, while the risk of intubation, number of days with oxygen, length of stay in ICU, and length of hospital stay were reduced. The main factors associated with early death among cancer patients was the severity of COVID-19 and the number of previous chemotherapy lines. The outcomes appear to be driven by the severity of the infection and therapeutic limitations decided at admission.

Indexed as

cancerCOVID-19matched cohort studymortalityprognosis

Identifiers

PMID34771446
PMCPMC8582532

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.