Evidence map›Paper›PMID 34771444›Full record

ArticleCancers2021

Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC-Spain Study.

Laura Álvarez-Álvarez, Facundo Vitelli-Storelli, María Rubín-García, Nuria Aragonés, Eva Ardanaz, Gemma Castaño-Vinyals, Mireia Obón-Santacana, Trinidad Dierssen-Sotos, Dolores Salas-Trejo, Adonina Tardón and 7 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Association between priori and posteriori dietary patterns and gastric cancer risk: an updated systematic review and meta-analysis of observational studies.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Observational
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 1 country.

Laura Álvarez-ÁlvarezGroup of Investigation in Interactions Gene-Environment and Health (GIIGAS), Institute of Biomedicine (IBIOMED), University of León, 24071 León, Spain.ORCID 0000-0002-4915-8314
Facundo Vitelli-StorelliGroup of Investigation in Interactions Gene-Environment and Health (GIIGAS), Institute of Biomedicine (IBIOMED), University of León, 24071 León, Spain.ORCID 0000-0002-3118-3570
María Rubín-GarcíaGroup of Investigation in Interactions Gene-Environment and Health (GIIGAS), Institute of Biomedicine (IBIOMED), University of León, 24071 León, Spain.ORCID 0000-0003-0916-4215
Nuria AragonésConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, Spain.
Eva ArdanazConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, Spain.
Gemma Castaño-VinyalsConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, Spain.ORCID 0000-0003-4468-1816
Mireia Obón-SantacanaOncology Data Analytics Program (ODAP), Catalan Institute of Oncology (ICO), L'Hospitalet Del Llobregat, 08908 Barcelona, Spain.
Trinidad Dierssen-SotosConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, Spain.
Dolores Salas-TrejoConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, Spain.
Adonina TardónConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, Spain.ORCID 0000-0001-5150-1209
José Juan Jiménez MoleónConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, Spain.ORCID 0000-0001-7917-6145
Juan AlguacilConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, Spain.
María Dolores ChirlaqueConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, Spain.
Beatriz Pérez-GómezConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, Spain.
Marina PollánConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, Spain.
Manolis KogevinasConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, Spain.
Vicente MartínGroup of Investigation in Interactions Gene-Environment and Health (GIIGAS), Institute of Biomedicine (IBIOMED), University of León, 24071 León, Spain.
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESUniversidad de León · ESInstituto de Salud Carlos III · ESBarcelona Institute for Global Health · ESCenter for Research in Environmental Epidemiology · ESGeneralitat Valenciana · ESInstitut Català d'Oncologia · ESInstituto Murciano de Investigación Biosanitaria · ESUniversidad de Cantabria · ESUniversidad de Granada · ESUniversidad de Oviedo · ES

Funding

Catalan Government- Agency for Management of University and Research Grants 2017SGR723 and 2014SGR850Consejería de Salud of the Junta de Andalucía PI-0571-2009, PI-0306-2011, salud201200057018traConselleria de Sanitat of the Generalitat Valenciana AP_061/10European Commission grants FOOD-CT-2006-036224-HIWATEFundación Marqués de Valdecilla API 10/09ICGC International Cancer Genome Consortium CLL RD12/0036/0036Instituto de Salud Carlos III-FEDER PI08/1770, PI08/0533, PI08/1359, PS09/00773-Cantabria, PS09/01286-León, PS09/01903-Valencia, PS09/02078-Huelva, PS09/01662-Granada, PI11/01403, PI11/01889-FEDER, PI11/00226, PI11/01810, PI11/02213, PI12/00488, PI12/00265, PI12/01270, PI12/00715, PI12/0015Junta de Castilla y León LE22A10-2Recercaixa 2010ACUP 00310Spanish Association Against Cancer GCTRA18022MORE
6 · The paper itself

Abstract

The aim was to assess the effect of adherence to the Mediterranean Diet, measured with five different indexes, on the risk of gastric cancer. Data come from the multicase-control study MCC-Spain, which included 354 gastric cancer cases and 3040 controls with data on diet. We used five indexes to evaluate adherence to the Mediterranean diet and assess the association between each pattern with the risk of gastric cancer, using multivariate logistic regression. The analyses were performed for the whole set of gastric cancer cases, by anatomical location (cardia and non-cardia) and by histological type (intestinal and diffuse). According to the used index, a high adherence protects one from gastric cancer (between 48% (aOR = 0.52; CI 95% = 0.28-0.94) and 75% (aOR = 0.25; CI 95% = 0.12-0.52)), from non-cardia (between 48% (aOR = 0.52; CI 95% = 0.36-0.75) and 65% (aOR = 0.35; CI 95% = 0.23-0.52)), and from the intestinal type (between 41% (aOR = 0.59; CI 95% = 0.36-0.95) and 72% (aOR = 0.28; CI 95% = 0.16-0.50)), but not from the diffuse type. In conclusion, high adherence to a Mediterranean diet pattern is a protective factor for the risk of gastric cancer, with greater adherence leading to greater protection.

Indexed as

dietfeeding behaviourMediterraneanstomach neoplasms

Identifiers

PMID34771444
PMCPMC8582518
OpenAlexW3207094579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.