ArticleCancers2021
The Impact of SARS-CoV-2 Pandemic on Time to Primary, Secondary Resection and Adjuvant Intravesical Therapy in Patients with High-Risk Non-Muscle Invasive Bladder Cancer: A Retrospective Multi-Institutional Cohort Analysis.
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Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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22citing papers in PubMed, 1 pooled it
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Oncologic outcomes of Bacillus Calmette-Guérin therapy in elderly patients with non-muscle-invasive bladder cancer: A meta-analysis.PloS one · 2022Pooled it
- Beyond the BCG Paradox: Biological Rationale and Clinical Evidence for Combining Intravesical BCG with Immune Checkpoint Inhibitors in High-Risk Non-muscle-Invasive Bladder Cancer.Oncology and therapy · 2026Review
- Article
- Awareness, knowledge, and willingness about early detection of bladder cancer in Saudi Arabia: a cross-sectional study.Translational andrology and urology · 2025Article
- Association Between Baseline Neutrophil-to-Lymphocyte Ratio and Short-Term Urinary Quality of Life During BCG Induction in Male Patients with Non-Muscle-Invasive Bladder Cancer: A Prospective Observational Study.Journal of clinical medicine · 2025Article
- Key strategies for reducing recurrence in T1 bladder cancer. Evidence from a retrospective multicenter European study.International urology and nephrology · 2025Article
- Tumor upgrading among very favorable intermediate-risk prostate cancer patients treated with robot-assisted radical prostatectomy: how can it impact the clinical course?International urology and nephrology · 2024Article
- Fear of progression after cancer recurrence: a mixed methods study.Frontiers in psychology · 2024Article
- Delays in diagnosis and surgery of sarcoma patients during the COVID-19 outbreak in Spain.Therapeutic advances in medical oncology · 2024Article
- Artificial Intelligence in the Advanced Diagnosis of Bladder Cancer-Comprehensive Literature Review and Future Advancement.Diagnostics (Basel, Switzerland) · 2023Review
- Emergency Urology procedures during the COVID-19 pandemic in the UK: A 3-month prospective study.Urologia · 2023Article
- Article
- The Impact of Covid-19 Pandemic on Genitourinary Cancers Stage and Grade.Clinical genitourinary cancer · 2023Article
- Intermediate and high-risk non-muscle-invasive bladder cancer: an overview of epidemiology, burden, and unmet needs.Frontiers in oncology · 2023Review
- The experience of UK patients with bladder cancer during the second wave of the COVID-19 pandemic.BJUI compass · 2022Article
- The delay in the diagnosis and treatment of newly diagnosed bladder cancer patients during COVID 19 pandemic.African health sciences · 2022Article
- BCG in Bladder Cancer Immunotherapy.Cancers · 2022Review
- Article
- Survival Outcome of Partial Cystectomy versus Transurethral Bladder Tumor Resection in T1 High-Grade Bladder Cancer Patients: A Propensity Score Matching Study.Journal of oncology · 2022Article
- Could We Safely Avoid a Second Resection in Selected Patients With T1 Non-Muscle-Invasive Bladder Cancer? Preliminary Results of Cost-Effectiveness Study From HUmanitas New Indications for ReTUR (HuNIRe) Multicenter Prospective Trial.Frontiers in oncology · 2022Article
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Authors and funding
59 authors at 20 institutions in 4 countries.
Matteo FerroDepartment of Urology, IEO European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141 Milan, Italy.ORCID 0000-0002-9250-7858
Francesco Del GiudiceDepartment of Urology, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0003-3865-5988
Giuseppe CarrieriUrology and Renal Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.
Gian Maria BusettoUrology and Renal Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0002-7291-0316
Luigi CormioUrology and Renal Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.
Rodolfo HurleDepartment of Urology, Humanitas Research Hospital, IRCCS, 20089 Milan, Italy.
Roberto ContieriDepartment of Urology, Humanitas Research Hospital, IRCCS, 20089 Milan, Italy.
Davide ArcanioloUnit of Urology, Luigi Vanvitelli University of Campania, 80138 Naples, Italy.
Alessandro SciarraDepartment of Urology, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.
Martina MaggiDepartment of Urology, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0003-4672-850X
Francesco PorpigliaDepartment of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, 10043 Turin, Italy.ORCID 0000-0001-8567-6795
Matteo ManfrediDepartment of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, 10043 Turin, Italy.
Cristian FioriDepartment of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, 10043 Turin, Italy.
Alessandro AntonelliDepartment of Urology, Ospedale Civile Maggiore, Polo Chirurgico Confortini, University of Verona, 37126 Verona, Italy.
Alessandro TafuriDepartment of Urology, Ospedale Civile Maggiore, Polo Chirurgico Confortini, University of Verona, 37126 Verona, Italy.
Pierluigi BoveDepartment of Urology, San Carlo di Nancy Hospital, Via Aurelia 275, 00165 Rome, Italy.
Carlo TerroneDepartment of Urology, Policlinico San Martino Hospital, University of Genoa, 16132 Genova, Italy.
Marco BorghesiDepartment of Urology, Policlinico San Martino Hospital, University of Genoa, 16132 Genova, Italy.
Elisabetta CostantiniAndrology and Urogynecology Clinic, Santa Maria Terni Hospital, University of Perugia, 05100 Terni, Italy.ORCID 0000-0001-9639-2886
Ester IlianoAndrology and Urogynecology Clinic, Santa Maria Terni Hospital, University of Perugia, 05100 Terni, Italy.
Emanuele MontanariUrology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Luca BoeriUrology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Giorgio Ivan RussoDepartment of Urology, University of Catania, 95124 Catania, Italy.
Massimo MadoniaUrologic Clinic, Department of Clinical and Experimental Medicine, University of Sassari, 07100 Sassari, Italy.
Alessandro TeddeUrologic Clinic, Department of Clinical and Experimental Medicine, University of Sassari, 07100 Sassari, Italy.
Alessandro VecciaDivision of Urology, VCU Health System, Richmond, VA 23298, USA.
Claudio SimeoneUrology Unit, Department of Medical and Surgical Specialties, Radiological Science and Public Health, University of Brescia, 25121 Brescia, Italy.
Giovanni LiguoriDepartment of Urology, ASUITS, University of Trieste, 34149 Trieste, Italy.
Carlo TrombettaDepartment of Urology, ASUITS, University of Trieste, 34149 Trieste, Italy.
Eugenio BrunocillaDepartment of Urology, University of Bologna, S-Orsola-Malpighi Hospital, 40138 Bologna, Italy.
Riccardo SchiavinaDepartment of Urology, University of Bologna, S-Orsola-Malpighi Hospital, 40138 Bologna, Italy.
Fabrizio Dal MoroUrology Unit, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padua, 35128 Padua, Italy.
Marco RacioppiUrology Clinic, A. Gemelli Hospital Foundation, Catholic University of the Sacred Heart, IRCCS, 00168 Rome, Italy.
Mihai Dorin VartolomeiUrology Department, Medical University of Vienna, A-1090 Vienna, Austria.
Nicola LongoUrology Unit, Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80131 Naples, Italy.
Lorenzo SpiritoUrology Unit, Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80131 Naples, Italy.
Felice CrocettoUrology Unit, Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-4315-7660
Francesco CantielloUrology Unit, Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80131 Naples, Italy.
Rocco DamianoDepartment of Urology, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy.
Savino M Di StasiDepartment of Surgery and Experimental Medicine, Tor Vergata University, 00133 Rome, Italy.
Michele MarchioniDepartment of Medical, Oral and Biotechnological Sciences, Urology Unit, "SS. Annunziata" Hospital, G. d'Annunzio University of Chieti, 66100 Chieti, Italy.
Luigi SchipsDepartment of Medical, Oral and Biotechnological Sciences, Urology Unit, "SS. Annunziata" Hospital, G. d'Annunzio University of Chieti, 66100 Chieti, Italy.
Paolo ParmaUrology Unit, Ospedale San Carlo Poma, 46100 Mantova, Italy.
Luca CarmignaniDepartment of Urology, San Donato Policlinic Hospital, 20094 Milan, Italy.
Andrea ContiDepartment of Urology, San Donato Policlinic Hospital, 20094 Milan, Italy.
Francesco SoriaDepartment of Surgical Sciences, Division of Urology, San Giovanni Battista Hospital, University of Studies of Torino, 10121 Turin, Italy.
Paolo GonteroDepartment of Surgical Sciences, Division of Urology, San Giovanni Battista Hospital, University of Studies of Torino, 10121 Turin, Italy.
Biagio BaroneUrology Unit, Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-4884-132X
Federico DehoUnit of Urology, ASST Sette Laghi-Circolo e Fondazione Macchi Hospital, 21100 Varese, Italy.
Emanuele ZaffutoUnit of Urology, ASST Sette Laghi-Circolo e Fondazione Macchi Hospital, 21100 Varese, Italy.
Rocco PapaliaDepartment of Urology, Campus Biomedico University Hospital, 00198 Rome, Italy.
Roberto M ScarpaDepartment of Urology, Campus Biomedico University Hospital, 00198 Rome, Italy.
Vincenzo PagliaruloUrology Unit, Ospedale Vito Fazzi, 73100 Lecce, Italy.
Giuseppe LucarelliUrology, Andrology and Kidney Transplantation Unit, Department of Emergency and Organ Transplantation, University of Bari, 70124 Bari, Italy.
Pasquale DitonnoUrology, Andrology and Kidney Transplantation Unit, Department of Emergency and Organ Transplantation, University of Bari, 70124 Bari, Italy.ORCID 0000-0001-7718-7676
Francesco Maria Gerardo BotticelliDepartment of Urology, IEO European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Gennaro MusiDepartment of Urology, IEO European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Michele CatellaniDepartment of Urology, IEO European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Ottavio de CobelliDepartment of Urology, IEO European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
University of Milan · ITUniversity of Naples Federico II · ITOspedale San Luigi Gonzaga · ITPoliclinico Umberto I · ITUniversity of Foggia · ITAzienda Ospedaliero Universitaria San Giovanni Battista · ITIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITIRCCS Humanitas Research Hospital · ITIRCCS Policlinico San Donato · ITOspedale di Circolo e Fondazione Macchi · ITOspedale Policlinico San Martino · ITOspedale San Carlo · ITUniversità Campus Bio-Medico · ITUniversity of Bari Aldo Moro · ITUniversity of Chieti-Pescara · ITUniversity of Perugia · ITUniversity of Sassari · ITUniversity of Trieste · ITUniversity of Verona · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · IT
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate the impact of COVID-19 outbreak on the diagnosis and treatment of non-muscle invasive bladder cancer (NMIBC).
methodsA retrospective analysis was performed using an Italian multi-institutional database of TURBT patients with high-risk urothelial NMIBC between January 2019 and February 2021, followed by Re-TURBT and/or adjuvant intravesical BCG.
resultsA total of 2591 patients from 27 institutions with primary TURBT were included. Of these, 1534 (59.2%) and 1056 (40.8%) underwent TURBT before and during the COVID-19 outbreak, respectively. Time between diagnosis and TURBT was significantly longer during the COVID-19 period (65 vs. 52 days,
conclusionsThe COVID-19 pandemic represented an unprecedented challenge to our health system. Our study did not show significant differences in TURBT quality. However, a delay in treatment schedule and disease management was observed. Investigation of the oncological impacts of those differences should be advocated.
Indexed as
bladder cancerintravesical BCGRe-TURBTSARS-CoV-2trans-urethral resection of bladder tumor
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