Evidence map›Paper›PMID 34771432›Full record

ReviewCancers2021

A Rational Approach to Unilateral Neck RT for Head and Neck Cancers in the Era of Immunotherapy.

Re-I Chin, Joshua P Schiff, Randall J Brenneman, Hiram A Gay, Wade L Thorstad, Alexander J Lin

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Re-I ChinDepartment of Radiation Oncology, Washington University School of Medicine, Saint Louis, MI 63110, USA.ORCID 0000-0003-2642-5712
Joshua P SchiffDepartment of Radiation Oncology, Washington University School of Medicine, Saint Louis, MI 63110, USA.
Randall J BrennemanDepartment of Radiation Oncology, Washington University School of Medicine, Saint Louis, MI 63110, USA.ORCID 0000-0001-6167-1746
Hiram A GayDepartment of Radiation Oncology, Washington University School of Medicine, Saint Louis, MI 63110, USA.
Wade L ThorstadDepartment of Radiation Oncology, Washington University School of Medicine, Saint Louis, MI 63110, USA.
Alexander J LinDepartment of Radiation Oncology, Washington University School of Medicine, Saint Louis, MI 63110, USA.ORCID 0000-0002-6971-7187
Washington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiotherapy plays an important role in the definitive and adjuvant treatment of head and neck squamous cell carcinoma (HNSCC). However, standard courses of radiation therapy may contribute to the depletion of circulating lymphocytes and potentially attenuate optimal tumor antigen presentation that may be detrimental to the efficacy of novel immunotherapeutic agents. This review explores the advantages of restricting radiation to the primary tumor/tumor bed and ipsilateral elective neck as it pertains to the evolving field of immunotherapy.

Indexed as

head and neck cancerimmunotherapyradiation therapyunilateral neck RT

Identifiers

PMID34771432
PMCPMC8582444
OpenAlexW3206550935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.