Evidence map›Paper›PMID 34771347›Full record

ReviewPolymers2021

Wound Healing with Electrical Stimulation Technologies: A Review.

Yt Jun Cheah, Muhamad Ramdzan Buyong, Mohd Heikal Mohd Yunus

Registry-linked trialAbstract readReview
In one paragraph

Review in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07465640 (Evaluating the Efficacy of Pulsating Electromagnetic Field), which is not on this map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07465640 narecruitingnot on this mapstarted 2026, after this paper: background citation

Evaluating the Efficacy of Pulsating Electromagnetic Field (PEMF) Therapy for Diabetic Foot Ulcers Using the CRAD ULCER X-01 Device: A Randomised Parallel-Group Pilot Study

TypeinterventionalSponsorNational Defence University of MalaysiaRan2026 to 2027Enrolled32ConditionsDiabetic Foot Ulcer, Diabetes Mellitus (DM)ArmsPulsating electromagnetic field
3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Electrical stimulation promotes longevity and regeneration in a colonial chordate.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Review
  8. Exploring New Horizons in Wound Healing: A Comprehensive Analysis.Recent advances in inflammation & allergy drug discovery · 2026
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Bioresorbable Materials for Wound Management.Biomimetics (Basel, Switzerland) · 2025
    Review
  18. Article
  19. Advances in electrical stimulation for wound healing.Frontiers in bioengineering and biotechnology · 2025
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yt Jun CheahDepartment of Physiology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur 56600, Malaysia.
Muhamad Ramdzan BuyongInstitute of Microengineering and Nanoelectronics, Universiti Kebangsaan Malaysia, Bangi 43600, Selangor, Malaysia.ORCID 0000-0003-4104-5320
Mohd Heikal Mohd YunusDepartment of Physiology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur 56600, Malaysia.

Funding

Ministry of Education Malaysia FRGS/1/2020/SKK0/UKM/02/6
6 · The paper itself

Abstract

Electrical stimulation (ES) is an attractive field among clinicians in the topic of wound healing, which is common yet complicated and requires multidisciplinary approaches. The conventional dressing and skin graft showed no promise on complete wound closure. These urge the need for the exploration of electrical stimulation to supplement current wound care management. This review aims to provide an overview of electrical stimulation in wound healing. The mechanism of galvanotaxis related to wound repair will be reviewed at the cellular and molecular levels. Meanwhile, different modalities of externally applied electricity mimicking a physiologic electric field will be discussed and compared in vitro, in vivo, and clinically. With the emerging of tissue engineering and regenerative medicine, the integration of electroconductive biomaterials into modern miniaturised dressing is of interest and has become possible with the advancing understanding of smart biomaterials.

Indexed as

electrical stimulationskintissue engineeringwound healing

Identifiers

PMID34771347
PMCPMC8588136

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.