Evidence map›Paper›PMID 34771282›Full record

ArticlePolymers2021

Channels with Helical Modulation Display Stereospecific Sensitivity for Chiral Superstructures.

Renáta Rusková, Dušan Račko

Abstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Renáta RuskováPolymer Institute, Slovak Academy of Sciences, Dúbravská Cesta 3, 84541 Bratislava, Slovakia.ORCID 0000-0002-8101-0993
Dušan RačkoPolymer Institute, Slovak Academy of Sciences, Dúbravská Cesta 3, 84541 Bratislava, Slovakia.ORCID 0000-0002-9203-9652

Funding

European Cooperation in Science and Technology CA 17139Grant Agency of the Ministry of Education, Science, Research and Sport of the Slovak Republic VEGA 2/0102/20Slovak Research and Development Agency SK-AT-20-0011
6 · The paper itself

Abstract

By means of coarse-grained molecular dynamics simulations, we explore chiral sensitivity of confining spaces modelled as helical channels to chiral superstructures represented by polymer knots. The simulations show that helical channels exhibit stereosensitivity to chiral knots localized on linear chains by effect of external pulling force and also to knots embedded on circular chains. The magnitude of the stereoselective effect is stronger for torus knots, the effect is weaker in the case of twist knots, and amphichiral knots do exhibit no chiral effects. The magnitude of the effect can be tuned by the so-far investigated radius of the helix, the pitch of the helix and the strength of the pulling force. The model is aimed to simulate and address a range of practical situations that may occur in experimental settings such as designing of nanotechnological devices for the detection of topological state of molecules, preparation of new gels with tailor made stereoselective properties, or diffusion of knotted DNA in biological conditions.

Indexed as

chiralitycoarse-grained simulationsconfinementDNAknotmolecular dynamicsnanochannelnanotechnologypolymertopology

Identifiers

PMID34771282
PMCPMC8588256

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.