Evidence map›Paper›PMID 34771112›Full record

ArticleMolecules (Basel, Switzerland)2021

Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays.

Lilian Mussi, André Rolim Baby, Flavio Bueno Camargo Junior, Giovana Padovani, Bianca da Silva Sufi, Wagner Vidal Magalhães

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Therapeutic Effect of Lecigel, CetiolInternational journal of molecular sciences · 2024
    Article
  2. Article
  3. Biological production of xylitol by using nonconventional microbial strains.World journal of microbiology & biotechnology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lilian MussiResearch and Development Department, Chemyunion Ltd., 18087-101 Sorocaba, Brazil.
André Rolim BabyDepartment of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil.ORCID 0000-0001-9197-3024
Flavio Bueno Camargo JuniorResearch and Development Department, Chemyunion Ltd., 18087-101 Sorocaba, Brazil.
Giovana PadovaniResearch and Development Department, Chemyunion Ltd., 18087-101 Sorocaba, Brazil.
Bianca da Silva SufiResearch and Development Department, Chemyunion Ltd., 18087-101 Sorocaba, Brazil.
Wagner Vidal MagalhãesResearch and Development Department, Chemyunion Ltd., 18087-101 Sorocaba, Brazil.
Chemyunion (Brazil) · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In addition to dermatological complications, acne can affect the quality of life of individuals in numerous ways, such as employment, social habits and body dissatisfaction. According to our expertise, caprylic acid and propanediol would not have a direct action on

Indexed as

Propylene GlycolsAcne VulgarisAnti-Bacterial AgentsAnti-Inflammatory AgentsCaprylatesClinical Trials as TopicDisease ManagementDisease SusceptibilityHumansMicrobial Sensitivity TestsStaphylococcus aureusTreatment OutcomeXylitolAnti-Bacterial AgentsAnti-Inflammatory AgentsCaprylatesoctanoic acidPropylene GlycolsXylitol5-alpha reductaseacnecaprylic acidefficacyporphyrinpropanediolsebum controlxylitol

Identifiers

PMID34771112
PMCPMC8587458
OpenAlexW3212309887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.