Evidence map›Paper›PMID 34771051›Full record

ArticleMolecules (Basel, Switzerland)2021

Berberine Derivatives as

Giorgia Giorgini, Gianmarco Mangiaterra, Nicholas Cedraro, Emiliano Laudadio, Giulia Sabbatini, Mattia Cantarini, Cristina Minnelli, Giovanna Mobbili, Emanuela Frangipani, Francesca Biavasco and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Discovery of Novel Molecular Scaffolds to OvercomeInternational journal of molecular sciences · 2026
    Article
  3. Research Status and Prospects ofGastroenterology research and practice · 2026
    Review
  4. Broadly Defined Antibiotic Adjuvants forThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Di-berberine conjugates as chemical probes ofbioRxiv : the preprint server for biology · 2023
    Article
  12. Review
  13. A Review ofMolecules (Basel, Switzerland) · 2023
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Giorgia GiorginiDepartment of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Gianmarco MangiaterraDepartment of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.ORCID 0000-0001-5035-5879
Nicholas CedraroDepartment of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Emiliano LaudadioDepartment of Materials, Environmental Sciences and Urban Planning, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.ORCID 0000-0002-8053-6539
Giulia SabbatiniDepartment of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Mattia CantariniDepartment of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Cristina MinnelliDepartment of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.ORCID 0000-0001-8034-8557
Giovanna MobbiliDepartment of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.ORCID 0000-0003-0243-5844
Emanuela FrangipaniDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.ORCID 0000-0001-5619-7912
Francesca BiavascoDepartment of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.ORCID 0000-0002-8582-2227
Roberta GaleazziDepartment of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.ORCID 0000-0003-1792-654X
Marche Polytechnic University · ITUniversity of Urbino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The natural alkaloid berberine has been demonstrated to inhibit the

Indexed as

Amino Acid SequenceAnti-Bacterial AgentsBacterial ProteinsBerberineBinding SitesChemistry Techniques, SyntheticDrug SynergismMicrobial Sensitivity TestsMolecular Docking SimulationMolecular Dynamics SimulationMolecular StructurePolymorphism, GeneticProtein BindingPseudomonas aeruginosaStructure-Activity RelationshipAnti-Bacterial AgentsBacterial ProteinsBerberineMexXY protein, Pseudomonas aeruginosaberberine derivativesefflux pump inhibitorsmolecular modelingmultidrug resistancePseudomonas aeruginosa

Identifiers

PMID34771051
PMCPMC8587913
OpenAlexW3209786867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.