Evidence map›Paper›PMID 34771045›Full record

ArticleMolecules (Basel, Switzerland)2021

Polyamines Upregulate Cephalosporin C Production and Expression of β-Lactam Biosynthetic Genes in High-Yielding

Alexander A Zhgun, Mikhail A Eldarov

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Comparative Proteomic Analysis ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  3. Comparative Genomic Analysis Reveals Key Changes in the Genome ofInternational journal of molecular sciences · 2024
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Microorganisms · 2022
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexander A ZhgunGroup of Fungal Genetic Engineering, Federal Research Center "Fundamentals of Biotechnology" of the Russian Academy of Sciences, 119071 Moscow, Russia.
Mikhail A EldarovGroup of Fungal Genetic Engineering, Federal Research Center "Fundamentals of Biotechnology" of the Russian Academy of Sciences, 119071 Moscow, Russia.
Russian Academy of Sciences · RU

Funding

Russian Foundation for Basic Research 19-04-01173
6 · The paper itself

Abstract

The high-yielding production of pharmaceutically significant secondary metabolites in filamentous fungi is obtained by random mutagenesis; such changes may be associated with shifts in the metabolism of polyamines. We have previously shown that, in the

Indexed as

beta-LactamsCephalosporinsGene Expression Regulation, FungalPenicillium chrysogenumPolyaminesSecondary Metabolismbeta-Lactamscephalosporin CCephalosporinsPolyaminesAcremonium chrysogenumbiosynthesis of secondary metabolitescephalosporin Cfilamentous fungipolyamines

Identifiers

PMID34771045
PMCPMC8588317
OpenAlexW3208823658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.