Evidence map›Paper›PMID 34771025›Full record

ArticleMolecules (Basel, Switzerland)2021

Amino Alcohols from Eugenol as Potential Semisynthetic Insecticides: Chemical, Biological, and Computational Insights.

Renato B Pereira, Nuno F S Pinto, Maria José G Fernandes, Tatiana F Vieira, Ana Rita O Rodrigues, David M Pereira, Sérgio F Sousa, Elisabete M S Castanheira, A Gil Fortes, M Sameiro T Gonçalves

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Development of eugenol derivatives with 5-LOX inhibitory activity.Journal of enzyme inhibition and medicinal chemistry · 2025
    Article
  2. Article
  3. Effect of Benzyl Alcohol on Main Defense System Components ofInternational journal of molecular sciences · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Eugenol β-Amino/β-Alkoxy Alcohols with Selective Anticancer Activity.International journal of molecular sciences · 2022
    Article
  8. Drug Repurposing TargetingAntibiotics (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Renato B PereiraREQUIMTE/LAQV, Laboratory of Pharmacognosy, Department of Chemistry, Faculty of Pharmacy, University of Porto, R. Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.ORCID 0000-0001-8500-7364
Nuno F S PintoCentre of Chemistry, Department of Chemistry, University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal.
Maria José G FernandesCentre of Chemistry, Department of Chemistry, University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal.
Tatiana F VieiraAssociate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.ORCID 0000-0001-5137-0798
Ana Rita O RodriguesCentre of Physics of Minho and Porto Universities (CF-UM-UP), University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0002-6094-1713
David M PereiraREQUIMTE/LAQV, Laboratory of Pharmacognosy, Department of Chemistry, Faculty of Pharmacy, University of Porto, R. Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.ORCID 0000-0003-0384-7592
Sérgio F SousaAssociate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.
Elisabete M S CastanheiraCentre of Physics of Minho and Porto Universities (CF-UM-UP), University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0002-5829-6081
A Gil FortesCentre of Chemistry, Department of Chemistry, University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal.
M Sameiro T GonçalvesCentre of Chemistry, Department of Chemistry, University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0003-2048-1190
University of Minho · PTUniversidade do Porto · PT

Funding

Fundação para a Ciência e Tecnologia CQ-UM (UID/QUI/00686/2020), CF-UM-UP (UIDB/04650/2020) and REQUIMTE (UIDB/50006/2020); REDE/1517/RMN/2005Fundação para a Ciência e Tecnologia PTDC/ASP-AGR/30154/2017 (POCI-01-0145-FEDER-030154)
6 · The paper itself

Abstract

A series of β-amino alcohols were prepared by the reaction of eugenol epoxide with aliphatic and aromatic amine nucleophiles. The synthesized compounds were fully characterized and evaluated as potential insecticides through the assessment of their biological activity against

Indexed as

Amino AlcoholsAnimalsApoptosisCells, CulturedCell SurvivalEugenolHumansInsecticidesModels, MolecularMolecular StructureSpodopteraAmino AlcoholsEugenolInsecticidesamino alcoholsbioinsecticidesbiopesticideseugenol derivativesphenylpropanoidssemisynthetic insecticidesSpodoptera frugiperda

Identifiers

PMID34771025
PMCPMC8587747
OpenAlexW3210150615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.