ArticleMolecules (Basel, Switzerland)2021
Synthesis of New Modified with Rhodamine B Peptides for Antiviral Protection of Textile Materials.
Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Anticonvulsant Profiles of Three Hemorphin-4 Analogs with Rhodamine B in Mice.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Novel Peptide Analogues of Valorphin-Conjugated 1,8-Naphthalimide as Photodynamic Antimicrobial Agent in Solution and on Cotton Fabric.Molecules (Basel, Switzerland) · 2024Article
- Recent Synthesis, Characterization, and Pharmacological Evaluation of Multifunctional Hemorphins Containing Non-Natural Amino Acids with Potential Biological Importance.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Synthesis, Characterization and Biological Investigation of New N-Modified Spinorphin Analogs.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Study of Novel Peptides for Antimicrobial Protection in Solution and on Cotton Fabric.Molecules (Basel, Switzerland) · 2022Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Here we report on the synthesis and characterization of three new N-modified analogues of hemorphin-4 with rhodamine B. Modified with chloroacetyl, chloride cotton fabric has been dyed and color coordinates of the obtained textile materials were determined. Antiviral and virucidal activities of both the peptide-rhodamine B compounds and the dyed textile material were studied. Basic physicochemical properties (acid-base behavior, solvent influence, kinetics) related to the elucidation of structural activity of the new modified peptides based on their steric open/closed ring effect were studied. The obtained results lead to the conclusion that in protic solvent with change in pH of the environment, direct control over the dyeing of textiles can be achieved. Both the new hybrid peptide compounds and the modification of functionalized textile materials with these bioactive hemorphins showed virucidal activity against the human respiratory syncytial virus (HRSV-S2) and human adenovirus serotype 5 (HAdV-5) for different time intervals (30 and 60 min) and the most active compound was Rh-3.
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Registered trials
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