Evidence map›Paper›PMID 34770878›Full record

ArticleMolecules (Basel, Switzerland)2021

Structural Characterization of Unusual Fatty Acid Methyl Esters with Double and Triple Bonds Using HPLC/APCI-MS

Petra Horká, Vladimír Vrkoslav, Jiří Kindl, Karolina Schwarzová-Pecková, Josef Cvačka

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Petra HorkáInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo Náměstí 542/2, 166 00 Prague 6, Czech Republic.
Vladimír VrkoslavInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo Náměstí 542/2, 166 00 Prague 6, Czech Republic.ORCID 0000-0002-5126-8360
Jiří KindlInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo Náměstí 542/2, 166 00 Prague 6, Czech Republic.
Karolina Schwarzová-PeckováDepartment of Analytical Chemistry, Faculty of Science, Charles University, Hlavova 2030/8, 128 43 Prague 2, Czech Republic.
Josef CvačkaInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo Náměstí 542/2, 166 00 Prague 6, Czech Republic.ORCID 0000-0002-3590-9009
Charles University · CZCzech Academy of Sciences, Institute of Organic Chemistry and Biochemistry · CZ

Funding

Charles University Grant Agency 10119Charles University in Prague SVV 260560European Regional Development Fund, OP RDE CZ.02.1.01/0.0/0.0/16_019/0000729
6 · The paper itself

Abstract

Double and triple bonds have significant effects on the biological activities of lipids. Determining multiple bond positions in their molecules by mass spectrometry usually requires chemical derivatization. This work presents an HPLC/MS method for pinpointing the double and triple bonds in fatty acids. Fatty acid methyl esters were separated by reversed-phase HPLC with an acetonitrile mobile phase. In the APCI source, acetonitrile formed reactive species, which added to double and triple bonds to form [M + C

Indexed as

AcetonitrilesAnimalsBeesChromatography, High Pressure LiquidEstersFatty AcidsMass SpectrometryMolecular StructureacetonitrileAcetonitrilesEstersFatty Acidsacetonitrile-related adductsacetylenic lipidsdouble and triple bond localizationin-source derivatizationmass spectrometry

Identifiers

PMID34770878
PMCPMC8588306
OpenAlexW3208400685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.