Evidence map›Paper›PMID 34770844›Full record

ArticleMolecules (Basel, Switzerland)2021

Synthesis and Toxicity Evaluation of New Pyrroles Obtained by the Reaction of Activated Alkynes with 1-Methyl-3-(cyanomethyl)benzimidazolium Bromide.

Beatrice-Cristina Ivan, Florea Dumitrascu, Adriana Iuliana Anghel, Robert Viorel Ancuceanu, Sergiu Shova, Denisa Dumitrescu, Constantin Draghici, Octavian Tudorel Olaru, George Mihai Nitulescu, Mihaela Dinu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Synthesis, Characterization and Cytotoxic Evaluation of New Pyrrolo[1,2-International journal of molecular sciences · 2023
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Beatrice-Cristina IvanFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.ORCID 0000-0001-6058-6347
Florea Dumitrascu"Costin D. Nenitescu" Center of Organic Chemistry, Romanian Academy, 202B Splaiul Independenței, 060023 Bucharest, Romania.
Adriana Iuliana AnghelFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.
Robert Viorel AncuceanuFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.
Sergiu ShovaLaboratory of Inorganic Polymers, "Petru Poni" Institute of Macromolecular Chemistry, 41A Aleea Grigore Ghica Voda, 700487 Iasi, Romania.ORCID 0000-0002-1222-4373
Denisa DumitrescuFaculty of Pharmacy, "Ovidius" University Constanta, Cpt. Av. Al. Serbanescu Street, 900470 Constanta, Romania.
Constantin Draghici"Costin D. Nenitescu" Center of Organic Chemistry, Romanian Academy, 202B Splaiul Independenței, 060023 Bucharest, Romania.
Octavian Tudorel OlaruFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.
George Mihai NitulescuFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.ORCID 0000-0002-2978-8052
Mihaela DinuFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.
Stefania-Felicia BarbuceanuFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · RORomanian Academy · ROOvidius University · RO

Funding

Carol Davila University of Medicine and Pharmacy Publish not Perish Grant.
6 · The paper itself

Abstract

A series of new pyrrole derivatives were designed as chemical analogs of the 1,4-dihydropyridines drugs in order to develop future new calcium channel blockers. The new tri- and tetra-substituted

Indexed as

AlkynesBenzimidazolesBromidesChemistry Techniques, SyntheticModels, MolecularMolecular StructurePyrrolesSpectrum AnalysisToxicity TestsToxicologyAlkynesBenzimidazolesBromidesPyrroles1,3-dipolar cycloadditionalkynesbenzimidazolium bromidepyrrolestoxicity evaluationX-ray diffraction

Identifiers

PMID34770844
PMCPMC8587665
OpenAlexW3209263980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.