Evidence map›Paper›PMID 34770797›Full record

ArticleMolecules (Basel, Switzerland)2021

In Vitro Effects of Papaverine on Cell Proliferation, Reactive Oxygen Species, and Cell Cycle Progression in Cancer Cells.

Daniella A Gomes, Anna M Joubert, Michelle H Visagie

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Redox Active Molecules in Cancer Treatments.Molecules (Basel, Switzerland) · 2023
    Article
  7. Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Daniella A GomesDepartment of Physiology, Faculty of Health Sciences, School of Medicine, University of Pretoria, Private Bag X323, Gezina, Pretoria 0031, South Africa.
Anna M JoubertDepartment of Physiology, Faculty of Health Sciences, School of Medicine, University of Pretoria, Private Bag X323, Gezina, Pretoria 0031, South Africa.ORCID 0000-0002-6931-7554
Michelle H VisagieDepartment of Physiology, Faculty of Health Sciences, School of Medicine, University of Pretoria, Private Bag X323, Gezina, Pretoria 0031, South Africa.ORCID 0000-0002-6820-7265
University of Pretoria · ZA

Funding

Cancer Association of South Africa A0V741 and A0W228National Research Foundation 99706National Research Foundation (South Africa) 105992, 90523 and 85818School of Medicine Research Committee, University of Pretoria AOSouth African Medical Research Council A0W110Struwig-Germeshuysen Kankernavorsingstrust AO
6 · The paper itself

Abstract

Papaverine (PPV) is an alkaloid isolated from the

Indexed as

ApoptosisCell CycleCell Line, TumorCell ProliferationCells, CulturedDose-Response Relationship, DrugHumansOxidative StressPapaverineReactive Oxygen SpeciesPapaverineReactive Oxygen Speciescancercell cyclemorphologypapaverineproliferation

Identifiers

PMID34770797
PMCPMC8587410
OpenAlexW3209388920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.