Evidence map›Paper›PMID 34770789›Full record

ReviewMolecules (Basel, Switzerland)2021

Carbonic Anhydrase Inhibitors and Epilepsy: State of the Art and Future Perspectives.

Lidia Ciccone, Chiara Cerri, Susanna Nencetti, Elisabetta Orlandini

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 87 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Introduction to Carbonic Anhydrase.Sub-cellular biochemistry · 2026
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Massive Activation of GABABiomolecules · 2025
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lidia CicconeDepartment of Pharmacy, University of Pisa, via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0002-2762-1929
Chiara CerriDepartment of Pharmacy, University of Pisa, via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0001-9930-7931
Susanna NencettiDepartment of Pharmacy, University of Pisa, via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0002-3547-7277
Elisabetta OrlandiniDepartment of Earth Sciences, University of Pisa, via Santa Maria 53, 56126 Pisa, Italy.
University of Pisa · IT

Funding

Ministry of Education, Universities and Research PRIN 2017SNRXH3
6 · The paper itself

Abstract

Carbonic anhydrases (CAs) are a group of ubiquitously expressed metalloenzymes that catalyze the reversible hydration/dehydration of CO

Indexed as

AnimalsBinding SitesCarbonic Anhydrase InhibitorsCarbonic AnhydrasesCatalysisClinical Trials as TopicDisease ManagementDisease SusceptibilityDrug DesignEpilepsyHumansIsoenzymesModels, MolecularProtein BindingStructure-Activity RelationshipTreatment OutcomeCarbonic Anhydrase InhibitorsCarbonic AnhydrasesIsoenzymesCA IICA inhibitors (CAIs)carbonic anhydrases (CAs)CA VIICA XIVepilepsy

Identifiers

PMID34770789
PMCPMC8588504
OpenAlexW3209466757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.