Evidence map›Paper›PMID 34770765›Full record

ArticleMolecules (Basel, Switzerland)2021

Design and Synthesis of Novel Betulin Derivatives Containing Thio-/Semicarbazone Moieties as Apoptotic Inducers through Mitochindria-Related Pathways.

Jiafeng Wang, Jiale Wu, Yinglong Han, Jie Zhang, Yu Lin, Haijun Wang, Jing Wang, Jicheng Liu, Ming Bu

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jiafeng WangCollege of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Jiale WuCollege of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Yinglong HanCollege of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Jie ZhangCollege of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Yu LinCollege of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Haijun WangCollege of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Jing WangCollege of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Jicheng LiuResearch Institute of Medicine & Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Ming BuCollege of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Qiqihar Medical University · CN

Funding

Central Government Support Fund for the Reform and Development of Local Universities-Talent Training Support Program Project ZYZX2019
6 · The paper itself

Abstract

Two new series of betulin derivatives with semicarbazone (

Indexed as

Chemistry Techniques, SyntheticDrug DesignAntineoplastic AgentsApoptosisBetulinic AcidBiomarkersCell Line, TumorCell ProliferationFlow CytometryHumansMembrane Potential, MitochondrialMetabolic Networks and PathwaysMitochondriaMolecular StructureReactive Oxygen SpeciesSemicarbazonesAntineoplastic AgentsbetulinBetulinic AcidBiomarkersReactive Oxygen SpeciesSemicarbazonesTriterpenesantitumorapoptosisbetulin derivativessemicarbazonethiosemicarbazone

Identifiers

PMID34770765
PMCPMC8587101
OpenAlexW3207215701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.