Evidence map›Paper›PMID 34770555›Full record

ArticleSensors (Basel, Switzerland)2021

A Generic Sequential Stimulation Adapter for Reducing Muscle Fatigue during Functional Electrical Stimulation.

Gongkai Ye, Saima S Ali, Austin J Bergquist, Milos R Popovic, Kei Masani

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Gongkai YeKITE-Toronto Rehabilitation Institute, University Health Network, Toronto, ON M4G 3V9, Canada.
Saima S AliDepartment of Electrical and Computer Engineering, University of Toronto, Toronto, ON M5S 3G4, Canada.
Austin J BergquistKITE-Toronto Rehabilitation Institute, University Health Network, Toronto, ON M4G 3V9, Canada.
Milos R PopovicKITE-Toronto Rehabilitation Institute, University Health Network, Toronto, ON M4G 3V9, Canada.
Kei MasaniKITE-Toronto Rehabilitation Institute, University Health Network, Toronto, ON M4G 3V9, Canada.ORCID 0000-0002-0207-3241
University Health Network · CAUniversity of Toronto · CA

Funding

CIHR PJT-148851
6 · The paper itself

Abstract

backgroundClinical applications of conventional functional electrical stimulation (FES) administered via a single electrode are limited by rapid onset neuromuscular fatigue. "Sequential" (SEQ) stimulation, involving the rotation of pulses between multiple active electrodes, has been shown to reduce fatigue compared to conventional FES. However, there has been limited adoption of SEQ in research and clinical settings.

methodsThe SEQ adapter is a small, battery-powered device that transforms the output of any commercially available electrical stimulator into SEQ stimulation. We examined the output of the adaptor across a range of clinically relevant stimulation pulse parameters to verify the signal integrity preservation ability of the SEQ adapter. Pulse frequency, amplitude, and duration were varied across discrete states between 4 and 200 Hz, 10 and100 mA, and 50 and 2000 μs, respectively.

resultsA total of 420 trials were conducted, with 80 stimulation pulses per trial. The SEQ adapter demonstrated excellent preservation of signal integrity, matching the pulse characteristics of the originating stimulator within 1% error. The SEQ adapter operates as expected at pulse frequencies up to 160 Hz, failing at a frequency of 200 Hz.

conclusionThe SEQ adapter represents an effective and low-cost solution to increase the utilization of SEQ in existing rehabilitation paradigms.

Indexed as

Electric Stimulation TherapyMuscle FatigueElectric StimulationElectrodesMuscle, Skeletalfatigue reductionfunctional electrical stimulationrehabilitationsequential stimulation

Identifiers

PMID34770555
PMCPMC8587998
OpenAlexW3208714659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.