Evidence map›Paper›PMID 34770340›Full record

ReviewSensors (Basel, Switzerland)2021

Application of Deep Learning Models for Automated Identification of Parkinson's Disease: A Review (2011-2021).

Hui Wen Loh, Wanrong Hong, Chui Ping Ooi, Subrata Chakraborty, Prabal Datta Barua, Ravinesh C Deo, Jeffrey Soar, Elizabeth E Palmer, U Rajendra Acharya

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hui Wen LohSchool of Science and Technology, Singapore University of Social Sciences, Singapore 599494, Singapore.
Wanrong HongCogninet Brain Team, Cogninet Australia, Sydney, NSW 2010, Australia.
Chui Ping OoiSchool of Science and Technology, Singapore University of Social Sciences, Singapore 599494, Singapore.ORCID 0000-0002-0293-3280
Subrata ChakrabortyFaculty of Engineering and Information Technology, University of Technology Sydney, Sydney, NSW 2007, Australia.ORCID 0000-0002-0102-5424
Prabal Datta BaruaCogninet Brain Team, Cogninet Australia, Sydney, NSW 2010, Australia.ORCID 0000-0001-5117-8333
Ravinesh C DeoSchool of Sciences, University of Southern Queensland, Springfield, QLD 4300, Australia.ORCID 0000-0002-2290-6749
Jeffrey SoarSchool of Business (Information Systems), Faculty of Business, Education, Law & Arts, University of Southern Queensland, Toowoomba, QLD 4350, Australia.ORCID 0000-0002-4964-7556
Elizabeth E PalmerCentre of Clinical Genetics, Sydney Children's Hospitals Network, Randwick, NSW 2031, Australia.
U Rajendra AcharyaSchool of Science and Technology, Singapore University of Social Sciences, Singapore 599494, Singapore.ORCID 0000-0003-2689-8552

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting over 6 million people globally. Although there are symptomatic treatments that can increase the survivability of the disease, there are no curative treatments. The prevalence of PD and disability-adjusted life years continue to increase steadily, leading to a growing burden on patients, their families, society and the economy. Dopaminergic medications can significantly slow down the progression of PD when applied during the early stages. However, these treatments often become less effective with the disease progression. Early diagnosis of PD is crucial for immediate interventions so that the patients can remain self-sufficient for the longest period of time possible. Unfortunately, diagnoses are often late, due to factors such as a global shortage of neurologists skilled in early PD diagnosis. Computer-aided diagnostic (CAD) tools, based on artificial intelligence methods, that can perform automated diagnosis of PD, are gaining attention from healthcare services. In this review, we have identified 63 studies published between January 2011 and July 2021, that proposed deep learning models for an automated diagnosis of PD, using various types of modalities like brain analysis (SPECT, PET, MRI and EEG), and motion symptoms (gait, handwriting, speech and EMG). From these studies, we identify the best performing deep learning model reported for each modality and highlight the current limitations that are hindering the adoption of such CAD tools in healthcare. Finally, we propose new directions to further the studies on deep learning in the automated detection of PD, in the hopes of improving the utility, applicability and impact of such tools to improve early detection of PD globally.

Indexed as

Deep LearningParkinson DiseaseArtificial IntelligenceGaitHumansSpeechcomputer-aided diagnosis (CAD)deep learningEEGgaithandwritingMRIParkinson’s disease (PD)PETSPECTspeech

Identifiers

PMID34770340
PMCPMC8587636

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.