Evidence map›Paper›PMID 34770252›Full record

ArticleSensors (Basel, Switzerland)2021

Cost-Effective Multiplex Fluorescence Detection System for PCR Chip.

Sung-Hun Yun, Ji-Sung Park, Seul-Bit-Na Koo, Chan-Young Park, Yu-Seop Kim, Jong-Dae Kim

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sung-Hun YunSchool of Software, Hallym University, Chuncheon-si 24252, Korea.
Ji-Sung ParkBiomedux Co., Ltd., Suwon-si 16226, Korea.
Seul-Bit-Na KooSchool of Software, Hallym University, Chuncheon-si 24252, Korea.
Chan-Young ParkSchool of Software, Hallym University, Chuncheon-si 24252, Korea.
Yu-Seop KimSchool of Software, Hallym University, Chuncheon-si 24252, Korea.
Jong-Dae KimSchool of Software, Hallym University, Chuncheon-si 24252, Korea.

Funding

Korea Health Industry Development Institute HW20C2053
6 · The paper itself

Abstract

The lack of portability and high cost of multiplex real-time PCR systems limits the device to be used in POC. To overcome this issue, this paper proposes a compact and cost-effective fluorescence detection system that can be integrated to a multiplex real-time PCR equipment. An open platform camera with embedded lens was used instead of photodiodes or an industrial camera. A compact filter wheel using a sliding tape is integrated, and the excitation LEDs are fixed at a 45° angle near the PCR chip, eliminating the need of additional filter wheels. The results show precise positioning of the filter wheel with an error less than 20 μm. Fluorescence detection results using a reference dye and standard DNA amplification showed comparable performance to that of the photodiode system.

Indexed as

Nucleic Acid Amplification TechniquesCost-Benefit AnalysisOligonucleotide Array Sequence AnalysisPolymerase Chain Reactionfilter wheelmultiplexopen platform cameraPCR chippoint of carereal-time PCR

Identifiers

PMID34770252
PMCPMC8588286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.