Evidence map›Paper›PMID 34769890›Full record

ReviewInternational journal of environmental research and public health2021

Redox Regulation and Oxidative Stress in Mammalian Oocytes and Embryos Developed

Madeleine L M Hardy, Margot L Day, Michael B Morris

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06261671 (Antioxidants-enriched Single-step vs Global Total Single-step Embryo Culture Media), which is not on this map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
18.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06261671 narecruitingnot on this mapstarted 2024, after this paper: background citation

Antioxidants-enriched Single-step vs Global Total Single-step Embryo Culture Media: Effect on Blastocyst Euploidy Rates.

TypeinterventionalSponsorART Fertility Clinics LLCRan2024 to 2025Enrolled500ConditionsInfertility, In Vitro FertilizationArmsantioxidants-enriched culture medium (Gx)
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 115 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Madeleine L M HardyDiscipline of Physiology, School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Sydney 2006, Australia.
Margot L DayDiscipline of Physiology, School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Sydney 2006, Australia.ORCID 0000-0002-8689-7458
Michael B MorrisDiscipline of Physiology, School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Sydney 2006, Australia.ORCID 0000-0002-1286-4784
The University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oocytes and preimplantation embryos require careful regulation of the redox environment for optimal development both

Indexed as

Embryonic DevelopmentOocytesAnimalsAntioxidantsOxidation-ReductionOxidative StressReactive Oxygen SpeciesAntioxidantsReactive Oxygen Speciesantioxidantsassisted reproductive technologyembryooocyteredoxROStransgenerational effects

Identifiers

PMID34769890
PMCPMC8583213
OpenAlexW3208001710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.