Evidence map›Paper›PMID 34769827›Full record

Observational studyInternational journal of environmental research and public health2021

Factors Associated with the Detection of Inappropriate Prescriptions in Older People: A Prospective Cohort.

Núria Molist-Brunet, Daniel Sevilla-Sánchez, Emma Puigoriol-Juvanteny, Mariona Espaulella-Ferrer, Jordi Amblàs-Novellas, Joan Espaulella-Panicot

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Núria Molist-BrunetHospital Universitari de la Santa Creu de Vic, 08500 Vic, Spain.ORCID 0000-0003-0138-6278
Daniel Sevilla-SánchezCentral Catalonia Chronicity Research Group (C3RG), Centre for Health and Social Care Research (CESS), Universitat de Vic. University of Vic-Central University of Catalonia (UVIC-UCC), 08500 Vic, Spain.ORCID 0000-0003-2993-6200
Emma Puigoriol-JuvantenyEpidemiology department. Hospital Universitari de Vic, 08500 Vic, Spain.ORCID 0000-0002-5510-2480
Mariona Espaulella-FerrerHospital Universitari de la Santa Creu de Vic, 08500 Vic, Spain.ORCID 0000-0003-3416-7792
Jordi Amblàs-NovellasHospital Universitari de la Santa Creu de Vic, 08500 Vic, Spain.ORCID 0000-0002-2338-3054
Joan Espaulella-PanicotHospital Universitari de la Santa Creu de Vic, 08500 Vic, Spain.ORCID 0000-0002-7057-0901
Universitat de Vic - Universitat Central de Catalunya · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Ageing is associated with complex and dynamic changes leading to multimorbidity and, therefore, polypharmacy. The main objectives were to study an older community-dwelling cohort, to detect inappropriate prescriptions (IP) applying the Patient-Centred Prescription model, and to evaluate the most associated factors. (2) Methods: This was a prospective, descriptive, and observational study conducted from June 2019 to October 2020 on patients ≥ 65 years with multimorbidity who lived in the community. Demographic, clinical and pharmacological data were assessed. Variables assessed were: degree of frailty, using the Frail-VIG index; therapeutical complexity and anticholinergic and sedative burden; and the number of chronic drugs to determine polypharmacy or excessive polypharmacy. Finally, a medication review was carried out through the application of the Patient-Centred Prescription model. We used univariate and multivariate regression to identify the factors associated with IP. (3) Results: We recruited 428 patients (66.6% women; mean age 85.5, SD 7.67). A total of 50.9% of them lived in a nursing home; the mean Barthel Index was 49.93 (SD 32.14), and 73.8% of patients suffered some degree of cognitive impairment. The prevalence of frailty was 92.5%. Up to 90% of patients had at least one IP. An increase in IP prevalence was detected when the Frail-VIG index increased (

Indexed as

FrailtyInappropriate PrescribingAgedAged, 80 and overCohort StudiesFemaleHumansMalePolypharmacyProspective Studiesfrailtygoal-oriented careinappropriate prescriptionmedication reviewmultimorbiditypolypharmacy

Identifiers

PMID34769827
PMCPMC8582657
OpenAlexW3209490892

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.