Evidence map›Paper›PMID 34769814›Full record

Trial reportInternational journal of environmental research and public health2021

Are Resistance Training-Induced BDNF in Hemodialysis Patients Associated with Depressive Symptoms, Quality of Life, Antioxidant Capacity, and Muscle Strength? An Insight for the Muscle-Brain-Renal Axis.

Lysleine Alves Deus, Hugo de Luca Corrêa, Rodrigo Vanerson Passos Neves, Andrea Lucena Reis, Fernando Sousa Honorato, Victor Lopes Silva, Michel Kendy Souza, Thaís Branquinho de Araújo, Lucas Santos de Gusmão Alves, Caio Victor Sousa and 6 more

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 9 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 9 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Lysleine Alves DeusGraduate Program in Physical Education, Catholic University of Brasília, Brasília 71966-700, Brazil.ORCID 0000-0001-5594-3717
Hugo de Luca CorrêaGraduate Program in Physical Education, Catholic University of Brasília, Brasília 71966-700, Brazil.ORCID 0000-0002-3080-9391
Rodrigo Vanerson Passos NevesGraduate Program in Physical Education, Catholic University of Brasília, Brasília 71966-700, Brazil.
Andrea Lucena ReisGraduate Program in Physical Education, Catholic University of Brasília, Brasília 71966-700, Brazil.
Fernando Sousa HonoratoGraduate Program in Physical Education, Catholic University of Brasília, Brasília 71966-700, Brazil.
Victor Lopes SilvaGraduate Program in Physical Education, Catholic University of Brasília, Brasília 71966-700, Brazil.
Michel Kendy SouzaDepartment of Nephrology, Federal University of São Paulo, São Paulo 04021-001, Brazil.
Thaís Branquinho de AraújoGraduate Program in Physical Education, Catholic University of Brasília, Brasília 71966-700, Brazil.
Lucas Santos de Gusmão AlvesGraduate Program in Medicine, Catholic University of Brasília, Brasília 71966-700, Brazil.
Caio Victor SousaBouve College of Health Sciences, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0002-0499-2372
Thaís Lucena ReisMedical Graduate Program, University of Brasília, Brasília 70910-900, Brazil.
Lucas Soares de AguiarMedical Graduate Program, University of Brasília, Brasília 70910-900, Brazil.
Herbert Gustavo SimõesGraduate Program in Physical Education, Catholic University of Brasília, Brasília 71966-700, Brazil.ORCID 0000-0002-2378-4026
Jonato PrestesGraduate Program in Physical Education, Catholic University of Brasília, Brasília 71966-700, Brazil.ORCID 0000-0003-0399-8817
Gislane Ferreira MeloGraduate Program in Physical Education, Catholic University of Brasília, Brasília 71966-700, Brazil.
Thiago Santos RosaGraduate Program in Physical Education, Catholic University of Brasília, Brasília 71966-700, Brazil.
Universidade Católica de Brasília · BRUniversidade de Brasília · BRNortheastern University · USUniversidade Federal de São Paulo · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

backgroundHemodialysis patients are suffering from depressive symptoms. Brain-derived neurotrophic factor (BDNF) levels are negatively associated with depressive symptoms and decrease during a single hemodialysis session. Resistance training (RT) might be an additional non-pharmacological tool to increase BDNF and promote mental health.

methodsTwo randomized groups of hemodialysis patients: control (CTL,

resultsRT improved handgrip strength (21.17 ± 4.38 vs. 27.17 ± 4.34;

conclusionsRT was effective as a non-pharmacological tool to increased BDNF levels, quality of life, temper the redox balance and decrease depressive symptoms intensity in hemodialysis patients.

Indexed as

AntioxidantsResistance TrainingBrainBrain-Derived Neurotrophic FactorDepressionHand StrengthHumansMusclesMuscle StrengthQuality of LifeRenal DialysisAntioxidantsBrain-Derived Neurotrophic Factordepressionneuroprotectionquality of liferedox balanceSF-36

Identifiers

PMID34769814
PMCPMC8583357
OpenAlexW3208697034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.