Evidence map›Paper›PMID 34769484›Full record

ArticleInternational journal of molecular sciences2021

A Novel Isogenic Human Cell-Based System for MEN1 Syndrome Generated by CRISPR/Cas9 Genome Editing.

Natalia Klementieva, Daria Goliusova, Julia Krupinova, Vladislav Yanvarev, Alexandra Panova, Natalia Mokrysheva, Sergey L Kiselev

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Aberrant Splicing ofInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Natalia KlementievaEndocrinology Research Centre, 115478 Moscow, Russia.ORCID 0000-0002-2742-372X
Daria GoliusovaVavilov Institute of General Genetics, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0003-2837-8868
Julia KrupinovaEndocrinology Research Centre, 115478 Moscow, Russia.
Vladislav YanvarevVavilov Institute of General Genetics, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0001-9896-6257
Alexandra PanovaEndocrinology Research Centre, 115478 Moscow, Russia.
Natalia MokryshevaEndocrinology Research Centre, 115478 Moscow, Russia.
Sergey L KiselevEndocrinology Research Centre, 115478 Moscow, Russia.
Endocrinology Research Center · RUVavilov Institute of General Genetics · RU

Funding

Russian Foundation for Basic Research 19-015-00209 a
6 · The paper itself

Abstract

Multiple endocrine neoplasia type 1 (MEN1) is a rare tumor syndrome that manifests differently among various patients. Despite the mutations in the

Indexed as

MutationAdultCells, CulturedCRISPR-Cas SystemsFemaleFibroblastsGene EditingHumansInduced Pluripotent Stem CellsMultiple Endocrine Neoplasia Type 1Proto-Oncogene ProteinsMEN1 protein, humanProto-Oncogene ProteinsCRISPR/Cas9 genome editingdefinitive endoderm differentiationinduced pluripotent stem cellsisogenic cell linesMEN1

Identifiers

PMID34769484
PMCPMC8584395
OpenAlexW3212146656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.