Evidence map›Paper›PMID 34769481›Full record

ArticleInternational journal of molecular sciences2021

Multi-Omics Study of Keystone Species in a Cystic Fibrosis Microbiome.

Cynthia B Silveira, Ana G Cobián-Güemes, Carla Uranga, Jonathon L Baker, Anna Edlund, Forest Rohwer, Douglas Conrad

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 25 citations in OpenAlex.

  1. Bridging bench and bedside: translational omics ofEuropean respiratory review : an official journal of the European Respiratory Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Cynthia B SilveiraDepartment of Biology, University of Miami, 1303 Memorial Dr., Coral Gables, FL 33146, USA.
Ana G Cobián-GüemesDepartment of Biology, San Diego State University, 5500 Campanile Dr., San Diego, CA 92182, USA.
Carla UrangaGenomic Medicine Group, J. Craig Venter Institute, San Diego, CA 92037, USA.
Jonathon L BakerGenomic Medicine Group, J. Craig Venter Institute, San Diego, CA 92037, USA.ORCID 0000-0001-5378-322X
Anna EdlundGenomic Medicine Group, J. Craig Venter Institute, San Diego, CA 92037, USA.
Forest RohwerDepartment of Biology, San Diego State University, 5500 Campanile Dr., San Diego, CA 92182, USA.
Douglas ConradDivision of Pulmonary, Critical Care and Sleep Medicine, University of California San Diego, San Diego, CA 92037, USA.
J. Craig Venter Institute · USSan Diego State University · USUniversity of California System · USUniversity of Miami · US

Funding

Cystic Fibrosis Research Inc. S00022215 to CSCystic Fibrosis Research Inc. S00023377 to FLRSpruance Foundation to FLR
6 · The paper itself

Abstract

Ecological networking and in vitro studies predict that anaerobic, mucus-degrading bacteria are keystone species in cystic fibrosis (CF) microbiomes. The metabolic byproducts from these bacteria facilitate the colonization and growth of CF pathogens like

Indexed as

MicrobiotaAdultAnti-Bacterial AgentsCystic FibrosisGenomicsHumansLungMaleMetabolomicsMetagenomicsRespiratory Function TestsRespiratory InsufficiencySputumAnti-Bacterial Agentsanaerobesclindamycinfermentationmetabolomicsmetagenomicsmucus plugstranscriptomicsWinCF

Identifiers

PMID34769481
PMCPMC8584531
OpenAlexW3212358354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.