Evidence map›Paper›PMID 34769453›Full record

ArticleInternational journal of molecular sciences2021

Stem Cell Therapy Enhances Motor Activity of Triceps Surae Muscle in Mice with Hereditary Peripheral Neuropathy.

Iryna Govbakh, Vitalii Kyryk, Alina Ustymenko, Volodymyr Rubtsov, Oleg Tsupykov, Nataliya V Bulgakova, Danylo O Zavodovskiy, Inna Sokolowska, Andriy Maznychenko

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Iryna GovbakhDepartment of General Practice-Family Medicine, Kharkiv Medical Academy of Postgraduate Education, 61000 Kharkiv, Ukraine.ORCID 0000-0002-5951-9806
Vitalii KyrykCell and Tissue Technologies Department, State Institute of Genetic and Regenerative Medicine NAMS of Ukraine, 04114 Kyiv, Ukraine.ORCID 0000-0001-7636-1302
Alina UstymenkoCell and Tissue Technologies Department, State Institute of Genetic and Regenerative Medicine NAMS of Ukraine, 04114 Kyiv, Ukraine.ORCID 0000-0002-0774-2109
Volodymyr RubtsovDepartment of Cytology, Histology and Reproductive Medicine, Educational and Scientific Institute of Biology and Medicine, Taras Shevchenko National University of Kyiv, 03127 Kyiv, Ukraine.
Oleg TsupykovCell and Tissue Technologies Department, State Institute of Genetic and Regenerative Medicine NAMS of Ukraine, 04114 Kyiv, Ukraine.ORCID 0000-0002-2107-651X
Nataliya V BulgakovaDepartment of Movement Physiology, Bogomoletz Institute of Physiology NAS of Ukraine, 01024 Kyiv, Ukraine.
Danylo O ZavodovskiyDepartment of Movement Physiology, Bogomoletz Institute of Physiology NAS of Ukraine, 01024 Kyiv, Ukraine.
Inna SokolowskaDepartment of Physical Education, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Andriy MaznychenkoDepartment of Movement Physiology, Bogomoletz Institute of Physiology NAS of Ukraine, 01024 Kyiv, Ukraine.ORCID 0000-0003-2312-4412
Bogomoletz Institute of Physiology · UAD.F. Chebotarev Institute of Gerontology · UAGdansk University of Physical Education and Sport · PLKharkiv Medical Academy of Postgraduate Education · UATaras Shevchenko National University of Kyiv · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Impaired motor and sensory functions are the main features of Charcot-Marie-Tooth disease. Mesenchymal stem cell (MSCs) therapy is one of the possible treatments for this disease. It was assumed that MSCs therapy can improve the contractile properties of the triceps surae (TS) muscles in mice with hereditary peripheral neuropathy. Murine adipose-derived mesenchymal stromal cells (AD-MSCs) were obtained for transplantation into TS muscles of

Indexed as

AnimalsCell- and Tissue-Based TherapyCharcot-Marie-Tooth DiseaseDisease Models, AnimalElectric StimulationMesenchymal Stem CellsMiceMice, Inbred C57BLMice, TransgenicMotor ActivityMuscle ContractionMuscle, SkeletalNerve Regenerationelectrical stimulationhereditary peripheral neuropathymicemuscle contractionstem cells

Identifiers

PMID34769453
PMCPMC8584487
OpenAlexW3213075896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.