Evidence map›Paper›PMID 34769425›Full record

ArticleInternational journal of molecular sciences2021

Decoding the Role of DVL1 in Intracranial Meningioma.

Anja Bukovac, Katarina Dragičević, Anja Kafka, Darko Orešković, Sanja Cesarec-Augustinović, Nives Pećina-Šlaus

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Anja BukovacLaboratory of Neurooncology, Croatian Institute for Brain Research, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0001-6587-8314
Katarina DragičevićBiotech Research & Innovation Centre, University of Copenhagen, DK-2200 Copenhagen, Denmark.ORCID 0000-0002-0214-9189
Anja KafkaLaboratory of Neurooncology, Croatian Institute for Brain Research, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Darko OreškovićDepartment of Neurosurgery, University Hospital Dubrava, 10000 Zagreb, Croatia.ORCID 0000-0003-3018-5248
Sanja Cesarec-Augustinović"Ljudevit Jurak" Department of Pathology and Cytology, Clinical Hospital Center "Sestre milosrdnice", 10000 Zagreb, Croatia.
Nives Pećina-ŠlausLaboratory of Neurooncology, Croatian Institute for Brain Research, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0002-3334-7671
University of Zagreb · HRSisters of Charity Hospital · HRUniversity Hospital Dubrava · HRUniversity of Copenhagen · DK

Funding

European Union GA KK01.1.1.01.0007
6 · The paper itself

Abstract

In the search for molecular candidates for targeted meningioma therapies, increasing attention has been paid to the role of signaling pathways in the development and progression of intracranial meningiomas. Although it is well known that the Wnt signaling pathway is involved in meningioma progression, the role of its central mediator, DVL1, is still unclear. In order to investigate the influence of

Indexed as

AdultAgedAged, 80 and overbeta CateninBiomarkers, TumorDishevelled ProteinsFemaleHumansMaleMeningeal NeoplasmsMeningiomaMicrosatellite InstabilityMiddle AgedMutationPDZ DomainsPrognosisbeta CateninBiomarkers, TumorCTNNB1 protein, humanDishevelled ProteinsDVL1 protein, humanDVL1intracranial meningiomaPDZ domainWnt signaling pathwayβ-catenin

Identifiers

PMID34769425
PMCPMC8584635
OpenAlexW3214340989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.