Evidence map›Paper›PMID 34769382›Full record

ArticleInternational journal of molecular sciences2021

Using Knock-Out Mutants to Investigate the Adhesion of

Christian Spengler, Friederike Nolle, Nicolas Thewes, Ben Wieland, Philipp Jung, Markus Bischoff, Karin Jacobs

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. ACS omega · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Christian SpenglerExperimental Physics and Center for Biophysics, Saarland University, 66123 Saarbrücken, Germany.ORCID 0000-0002-0504-1149
Friederike NolleExperimental Physics and Center for Biophysics, Saarland University, 66123 Saarbrücken, Germany.ORCID 0000-0002-8270-0216
Nicolas ThewesExperimental Physics and Center for Biophysics, Saarland University, 66123 Saarbrücken, Germany.
Ben WielandInstitute of Medical Microbiology and Hygiene and Center for Biophysics, Saarland University, 66421 Homburg, Germany.ORCID 0000-0003-1917-7095
Philipp JungInstitute of Medical Microbiology and Hygiene and Center for Biophysics, Saarland University, 66421 Homburg, Germany.ORCID 0000-0001-6182-6592
Markus BischoffInstitute of Medical Microbiology and Hygiene and Center for Biophysics, Saarland University, 66421 Homburg, Germany.
Karin JacobsExperimental Physics and Center for Biophysics, Saarland University, 66123 Saarbrücken, Germany.ORCID 0000-0002-2963-2533
Institute of Medical Microbiology and Hygiene · DESaarland University · DEMax Planck School Matter to Life

Funding

Deutsche Forschungsgemeinschaft 449375068Deutsche Forschungsgemeinschaft JA 905/6Deutsche Forschungsgemeinschaft SFB 1027
6 · The paper itself

Abstract

The adhesion of

Indexed as

Bacterial AdhesionBiofilmsHydrophobic and Hydrophilic InteractionsSiliconStaphylococcus aureusSurface PropertiesSiliconbacterial adhesionhydrophobicitysingle-cell force spectroscopyStaphylococcus aureusStaphylococcus aureus knock-out mutantssurface charge

Identifiers

PMID34769382
PMCPMC8584566
OpenAlexW3210092651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.