Evidence map›Paper›PMID 34769345›Full record

ArticleInternational journal of molecular sciences2021

Adhesive Antimicrobial Peptides Containing 3,4-Dihydroxy-L-Phenylalanine Residues for Direct One-Step Surface Coating.

Young Eun Hwang, Seonghun Im, Hyun Kim, Jung-Hoon Sohn, Byung-Kwan Cho, Ju Hyun Cho, Bong Hyun Sung, Sun Chang Kim

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Exploring the Potential of a Genome-ReducedInternational journal of molecular sciences · 2023
    Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Young Eun HwangDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.ORCID 0000-0002-3522-5731
Seonghun ImSynthetic Biology and Bioengineering Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.
Hyun KimDivision of Applied Life Science (BK21Four), Research Institute of Life Sciences, Gyeongsang National University, Jinju 52828, Korea.
Jung-Hoon SohnSynthetic Biology and Bioengineering Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.
Byung-Kwan ChoDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.
Ju Hyun ChoDivision of Applied Life Science (BK21Four), Research Institute of Life Sciences, Gyeongsang National University, Jinju 52828, Korea.
Bong Hyun SungSynthetic Biology and Bioengineering Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.
Sun Chang KimDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial colonization and transmission via surfaces increase the risk of infection. In this study, we design and employ novel adhesive antimicrobial peptides to prevent bacterial contamination of surfaces. Repeats of 3,4-dihydroxy-L-phenylalanine (DOPA) were added to the C-terminus of NKC, a potent synthetic antimicrobial peptide, and the adhesiveness and antibacterial properties of the resulting peptides are evaluated. The peptide is successfully immobilized on polystyrene, titanium, and polydimethylsiloxane surfaces within 10 min in a one-step coating process with no prior surface functionalization. The antibacterial effectiveness of the NKC-DOPA

Indexed as

Anti-Bacterial AgentsAntimicrobial PeptidesEscherichia coliHumansPhenylalaninePseudomonas aeruginosaStaphylococcus aureusAnti-Bacterial AgentsAntimicrobial PeptidesPhenylalanineantimicrobial peptidecoatinginfectionin vivo bactericidal activityL-DOPA

Identifiers

PMID34769345
PMCPMC8584447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.