Evidence map›Paper›PMID 34769340›Full record

ReviewInternational journal of molecular sciences2021

Tapping into 5-HT

Helen Irving, Ilona Turek, Christine Kettle, Nor Yaakob

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Predicted conformations of 5-HT3 receptor ion channels are modified by subunit D.Computational and structural biotechnology journal · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. 5-HTInternational journal of molecular sciences · 2023
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Helen IrvingDepartment of Pharmacy and Biomedical Sciences, La Trobe Institute for Molecular Science, La Trobe University, Bendigo, VIC 3550, Australia.ORCID 0000-0002-1514-0909
Ilona TurekDepartment of Pharmacy and Biomedical Sciences, La Trobe Institute for Molecular Science, La Trobe University, Bendigo, VIC 3550, Australia.ORCID 0000-0001-6457-7456
Christine KettleDepartment of Pharmacy and Biomedical Sciences, La Trobe Institute for Molecular Science, La Trobe University, Bendigo, VIC 3550, Australia.ORCID 0000-0003-3223-4090
Nor YaakobDrug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur 50300, Malaysia.
La Trobe University · AUNational University of Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

5-hydroxytryptamine type 3 (5-HT

Indexed as

AnimalsHumansImmunityInflammationMetabolic DiseasesReceptors, Serotonin, 5-HT3Serotonin 5-HT3 Receptor AntagonistsReceptors, Serotonin, 5-HT3Serotonin 5-HT3 Receptor Antagonists5-HT3 receptor-based therapies5-hydroxytryptamine receptorsadipose tissuechemotherapy induced vomiting and emesis (CINV)HTR3 single nucleotide polymorphismHTR3 variant associationsinflammationmetabolismserotonin receptors

Identifiers

PMID34769340
PMCPMC8584345
OpenAlexW3209972844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.