Evidence map›Paper›PMID 34769232›Full record

ArticleInternational journal of molecular sciences2021

Cell Cycle Regulation of Hippocampal Progenitor Cells in Experimental Models of Depression and after Treatment with Fluoxetine.

Patrícia Patrício, António Mateus-Pinheiro, Ana Rita Machado-Santos, Nuno Dinis Alves, Joana Sofia Correia, Mónica Morais, João Miguel Bessa, Ana João Rodrigues, Nuno Sousa, Luísa Pinto

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Patrícia PatrícioLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
António Mateus-PinheiroLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
Ana Rita Machado-SantosLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
Nuno Dinis AlvesLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
Joana Sofia CorreiaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
Mónica MoraisLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
João Miguel BessaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
Ana João RodriguesLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
Nuno SousaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.
Luísa PintoLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0002-7724-0446
University of Minho · PTNew York Psychoanalytic Society and Institute · US

Funding

ATTENTION, COGNITION AND DRIVING PERFORMANCE IN SDATR01AG010145 · NIA · JEWISH HOSPITAL OF SAINT LOUIS · PI MORRIS, JOHN · 1992 to 1994
–
FEDER, through the Competitiveness Internationalization Operational Program (POCI) UIDB/50026/2020; UIDP/50026/2020; NORTE-01-0145-FEDER-000013; NORTE-01-0145-FEDER-000023Fundação para a Ciência e Tecnologia IF/01079/2014; 2020.02855.CEECINDNature Research Award for Driving Global Impact - 2019 Brain Sciences LPPPBI - Portuguese Platform of Bioimaging PPBI-POCI-01-0145-FEDER-022122
6 · The paper itself

Abstract

Changes in adult hippocampal cell proliferation and genesis have been largely implicated in depression and antidepressant action, though surprisingly, the underlying cell cycle mechanisms are largely undisclosed. Using both an

Indexed as

DepressionAnimalsCyclinsDexamethasoneDisease Models, AnimalFluoxetineG1 Phase Cell Cycle CheckpointsHippocampusMaleNeural Stem CellsRatsSerotoninCyclinsDexamethasoneFluoxetineSerotoninantidepressantscell cycledepressionhippocampal cytogenesisunpredictable chronic mild stress

Identifiers

PMID34769232
PMCPMC8584049
OpenAlexW3210100972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.