Evidence map›Paper›PMID 34769190›Full record

ArticleInternational journal of molecular sciences2021

Characterizing SERCA Function in Murine Skeletal Muscles after 35-37 Days of Spaceflight.

Jessica L Braun, Mia S Geromella, Sophie I Hamstra, Holt N Messner, Val A Fajardo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jessica L BraunDepartment of Kinesiology, Brock University, St. Catharines, ON L2S 3A1, Canada.ORCID 0000-0002-9196-0757
Mia S GeromellaDepartment of Kinesiology, Brock University, St. Catharines, ON L2S 3A1, Canada.
Sophie I HamstraDepartment of Kinesiology, Brock University, St. Catharines, ON L2S 3A1, Canada.
Holt N MessnerDepartment of Kinesiology, Brock University, St. Catharines, ON L2S 3A1, Canada.
Val A FajardoDepartment of Kinesiology, Brock University, St. Catharines, ON L2S 3A1, Canada.ORCID 0000-0003-4500-3347
Brock University · CA

Funding

Brock University Unrestricted GrantCanada Research Chairs VAF
6 · The paper itself

Abstract

It is well established that microgravity exposure causes significant muscle weakness and atrophy via muscle unloading. On Earth, muscle unloading leads to a disproportionate loss in muscle force and size with the loss in muscle force occurring at a faster rate. Although the exact mechanisms are unknown, a role for Ca

Indexed as

AnimalsCalciumFemaleMaleMiceMice, Inbred C57BLMuscle, SkeletalSarcoplasmic Reticulum Calcium-Transporting ATPasesSpace FlightWeightlessnessAtp2a1 protein, mouseAtp2a2 protein, mouseCalciumSarcoplasmic Reticulum Calcium-Transporting ATPasescalcium ATPasecalcium handlingmuscle fiber typeneuronatinphospholambansarcolipinsarcoplasmic reticulumspaceflightunloading

Identifiers

PMID34769190
PMCPMC8584217
OpenAlexW3208293956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.