Evidence map›Paper›PMID 34769181›Full record

ArticleInternational journal of molecular sciences2021

Panx1b Modulates the Luminance Response and Direction of Locomotion in the Zebrafish.

Nickie Safarian, Sarah Houshangi-Tabrizi, Christiane Zoidl, Georg R Zoidl

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nickie SafarianDepartment of Biology, York University, Toronto, ON M3J 1P3, Canada.
Sarah Houshangi-TabriziDepartment of Biology, York University, Toronto, ON M3J 1P3, Canada.
Christiane ZoidlDepartment of Biology, York University, Toronto, ON M3J 1P3, Canada.
Georg R ZoidlDepartment of Biology, York University, Toronto, ON M3J 1P3, Canada.ORCID 0000-0003-1163-3260

Funding

Natural Sciences and Engineering Research Council (NSERC) Discovery grant RGPIN - 418142-2012 (GRZ)
6 · The paper itself

Abstract

Pannexin1 (Panx1) can form ATP-permeable channels that play roles in the physiology of the visual system. In the zebrafish two ohnologs of Panx1, Panx1a and Panx1b, have unique and shared channel properties and tissue expression patterns. Panx1a channels are located in horizontal cells of the outer retina and modulate light decrement detection through an ATP/pH-dependent mechanisms and adenosine/dopamine signaling. Here, we decipher how the strategic localization of Panx1b channels in the inner retina and ganglion cell layer modulates visually evoked motor behavior. We describe a

Indexed as

Motion PerceptionSwimmingVision, OcularAnimalsConnexinsRNA-SeqZebrafishZebrafish ProteinsConnexinspanx1a protein, zebrafishZebrafish Proteinsbehaviorcircadian clockMuller gliapannexin1bretinal ganglion cellstranscriptomicsvisual systemzebrafish

Identifiers

PMID34769181
PMCPMC8584175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.